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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jul 16, 2025; 17(7): 106725
Published online Jul 16, 2025. doi: 10.4253/wjge.v17.i7.106725
Published online Jul 16, 2025. doi: 10.4253/wjge.v17.i7.106725
Hemostasis: Role of PuraStat® in the prevention and management of gastrointestinal bleeding
Samy A Azer, Department of Medical Education and Medicine, College of Medicine at King Saud University, Riyadh 11461, Riyadh, Saudi Arabia
Author contributions: Azer SA has searched the literature on several databases, top journals in gastroenterology and others, extracted papers related to the topic, read and organised the outcomes from the literature, studied the paper to write the editorial on, drafted the first part of the editorial, revised and amended based on the literature and research evidence, and then created the final manuscript after several revisions and changes.
Conflict-of-interest statement: The author has no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Samy A Azer, Professor, Department of Medical Education and Medi cine, College of Medicine at King Saud University, PO Box 2925, Riyadh 11461, Riyadh, Saudi Arabia. azer2000@optusnet.com.au
Received: March 6, 2025
Revised: May 4, 2025
Accepted: June 24, 2025
Published online: July 16, 2025
Processing time: 125 Days and 23 Hours
Revised: May 4, 2025
Accepted: June 24, 2025
Published online: July 16, 2025
Processing time: 125 Days and 23 Hours
Core Tip
Core Tip: Patients experiencing upper or lower gastrointestinal (GI) bleeding, whether due to a medical condition or an endoscopic procedure, should be managed immediately using a simple, effective and safe agent or technique. PuraStat® (TDM-621) is a novel transparent, self-assembled hydro-peptide gel with a hemostatic effect that has been used in endo