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Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Nov 16, 2025; 17(11): 112247
Published online Nov 16, 2025. doi: 10.4253/wjge.v17.i11.112247
Diagnosis and management of a rare case of esophageal epidermoid metaplasia: A case report
Arvinf Rajandran, Anthony Sakiris, Sneha John
Arvinf Rajandran, Anthony Sakiris, Sneha John, Department of Gastroenterology, Gold Coast University Hospital, Southport 4060, Queensland, Australia
Author contributions: Rajandran A lead the conceptualization and drafting of the manuscript; Rajandran A, Sakiris A and John S contributed to the review and editing of all subsequent versions of the manuscript; Rajandran A and Sakiris A contributed to visualisation of the data; John S lead the supervision of the project and validation of the data.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: No conflicts of interest to disclose for all authors.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Arvinf Rajandran, MD, Department of Gastroenterology, Gold Coast University Hospital, 1 Hospital Blvd, Southport 4060, Queensland, Australia. arvinf.rajandran@health.qld.gov.au
Received: July 22, 2025
Revised: August 26, 2025
Accepted: September 28, 2025
Published online: November 16, 2025
Processing time: 115 Days and 17.8 Hours
Core Tip

Core Tip: Is there any role as premalignant: A precursor to esophageal squamous cell carcinoma and dysplasia? Esophageal epidermoid metaplasia (EEM) is a rare but potentially premalignant oesophageal lesion. There remains a paucity of data on the formal management of EEM, likely due to the heterogeneity in the presentation, characterisation and detection of EEM. The decision for endoscopic resection vs conservative management is highly individualised. We highlight this case with the aim to increase awareness and detection rate.