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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Nov 16, 2025; 17(11): 110082
Published online Nov 16, 2025. doi: 10.4253/wjge.v17.i11.110082
Published online Nov 16, 2025. doi: 10.4253/wjge.v17.i11.110082
Endoscopic resection of colitis-associated neoplasia: A scoping review
Partha Pal, Zaheer Nabi, Mohan Ramchandani, Rajesh Gupta, Manu Tandan, Nageshwar Reddy Duvvur, Department of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, Telangana, India
Priyaranjan Kata, Department of Medicine, MedStar St. Mary’s Hospital, Leonardtown, MD 20650, United States
Co-first authors: Partha Pal and Priyaranjan Kata.
Author contributions: Pal P conceptualized the work, performed the literature search, wrote the first draft, and provided intellectual input; Kata P conducted the first screening and carried out critical manuscript review; Pal P and Kata P contributed equally to this article, they are the co-first authors of this manuscript; Nabi Z and Ramchandani M provided intellectual input and critically revised the manuscript; Gupta R and Tandan M each supervised the literature search and manuscript writing, while also providing intellectual input and critically revising the manuscript; Duvvur NR supervised the manuscript writing, provided intellectual input, and critically revised the manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Conflict-of-interest statement: Partha Pal has received consultancy fees from Johnson and Johnson, other authors have no relevant conflicts of interest to disclose.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Partha Pal, MD, FASGE, MRCP, Department of Medical Gastroen
Received: May 28, 2025
Revised: June 18, 2025
Accepted: October 9, 2025
Published online: November 16, 2025
Processing time: 169 Days and 19.1 Hours
Revised: June 18, 2025
Accepted: October 9, 2025
Published online: November 16, 2025
Processing time: 169 Days and 19.1 Hours
Core Tip
Core Tip: Endoscopic resection techniques - polypectomy, mucosal resection, submucosal dissection, and full-thickness resection - offer organ-sparing options for dysplasia in ulcerative colitis. Technique selection should be guided by lesion morphology, location, response to lifting, and degree of fibrosis. Submucosal dissection is preferred for flat, fibrotic, or non-lifting lesions, while mucosal resection suits well-lifting, polypoid lesions. Adjuncts such as water pressure dissection, peptide-based injectables, and traction systems enhance technical success. Full-thickness resection is a valuable option for non-lifting or scarred lesions not amenable to conventional methods, though careful case selection is essential.