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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Oct 16, 2025; 17(10): 110417
Published online Oct 16, 2025. doi: 10.4253/wjge.v17.i10.110417
Published online Oct 16, 2025. doi: 10.4253/wjge.v17.i10.110417
Sessile serrated lesions involving the appendiceal orifice: Endoscopic diagnosis and treatment
Meng-Yuan Zhang, Jing-Jing Yao, Sheng-Xue Pan, Wen-Wen Hou, Xin Wei, Xiang-Lu Zhao, Jin-Dong Fu, Department of Gastroenterology, The People’s Hospital of Rizhao, Rizhao 276800, Shandong Province, China
Author contributions: Zhang MY performed the majority of the writing; Yao JJ and Fu JD prepared the figures and tables; Pan SX, Hou WW, Wei X, and Zhao XL contributed to the writing of the manuscript; All authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Dong Fu, Chief Physician, Department of Gastroenterology, The People’s Hospital of Rizhao, No. 126 Taian Road, Rizhao 276800, Shandong Province, China.
Received: June 6, 2025
Revised: June 25, 2025
Accepted: September 17, 2025
Published online: October 16, 2025
Processing time: 132 Days and 17.3 Hours
Revised: June 25, 2025
Accepted: September 17, 2025
Published online: October 16, 2025
Processing time: 132 Days and 17.3 Hours
Core Tip
Core Tip: The application of endoscopic full-thickness resection has enabled the feasibility of endoscopic appendectomy. When combined with choledochoscopy, it further enhances the accuracy of the procedure. This integrated approach offers a novel therapeutic strategy for sessile serrated lesions involving the appendix, potentially replacing the combination of endoscopy and laparoscopy. Future validation of its safety and reliability will depend on additional follow-up data.