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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Oct 16, 2025; 17(10): 110116
Published online Oct 16, 2025. doi: 10.4253/wjge.v17.i10.110116
Published online Oct 16, 2025. doi: 10.4253/wjge.v17.i10.110116
Endoscopic treatment of large colorectal lesions: A retrospective analysis of efficacy and safety
Wen-Wen Zhu, Xin Yang, Zhuo Yang, Jiao Liu, Wen Jia, Xu-Lin Chen, Ye Tian, Teng-Jiao Gao, Guo-Yao Sun, Meng Zhang, Jing-Yi Yu, Jian-Feng Huo, Huan-Nan Zhao, Department of Endoscopy, General Hospital of Northern Theater Command, Shenyang 110011, Liaoning Province, China
Chuan-Hong Liu, Department of Outpatient, The First Cadre’s Sanitarium of Liaoning Military Command, Shenyang 110016, Liaoning Province, China
Co-first authors: Wen-Wen Zhu and Xin Yang.
Author contributions: Zhu WW and Yang X participated in the conception, design of the study, involved in the acquisition, analysis, and interpretation of data, they contributed equally to this manuscript and are co-first authors; Zhu WW wrote the manuscript; Yang Z, Liu J and Jia W accessed and verified the study data; Chen XL, Tian Y, Gao TJ and Sun GY were responsible for patient screening, enrollment and collection of clinical data; Zhang M, Yu JY, Huo JF, Zhao HN were responsible for study supervision, manuscript revision and submission. All authors critically reviewed and provided final approval of the manuscript; and all authors were responsible for the decision to submit the manuscript for publication.
Supported by the Shenyang Science and Technology of Liaoning Province, No. 22-321-32-15.
Institutional review board statement: This study was approved by the Ethics Committee of General Hospital of Northern Theater Command, No. Y (2025) 073.
Informed consent statement: The need for patient consent was waived due to the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhuo Yang, Chief Physician, Professor, Department of Endoscopy, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenhe District, Shenyang 110011, Liaoning Province, China. yangzhuocy@163.com
Received: May 30, 2025
Revised: June 17, 2025
Accepted: September 18, 2025
Published online: October 16, 2025
Processing time: 140 Days and 4.5 Hours
Revised: June 17, 2025
Accepted: September 18, 2025
Published online: October 16, 2025
Processing time: 140 Days and 4.5 Hours
Core Tip
Core Tip: This single-center retrospective study evaluated the efficacy and safety of endoscopic resection for large colorectal lesions. Results demonstrated that lesion diameter does not constitute an absolute contraindication to endoscopic therapy, with complete resection achievable in experienced centers. Critically, lesion location in the transverse colon was identified as an independent risk factor for post-endoscopic submucosal dissection electrocoagulation syndrome.