Zhang JC, Ma YY, Lan YZ, Li SB, Wang X, Hu JL. Evaluation of appendiceal mucinous neoplasms by curved linear-array echoendoscope: A preliminary study. World J Gastrointest Endosc 2023; 15(12): 699-704 [PMID: 38187914 DOI: 10.4253/wjge.v15.i12.699]
Corresponding Author of This Article
Jin-Long Hu, PhD, Doctor, Department of Gastroenterology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110001, Liaoning Province, China. 360484590@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jing-Chao Zhang, Yong-Zhen Lan, Xiao Wang, Endoscopy Center, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Yang-Yang Ma, Department of Gastrointestinal Surgery, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Shuang-Biao Li, Department of Pathology, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Jin-Long Hu, Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: Hu JL, Zhang JC, Ma YY, and Lan YZ designed and performed the research study; Hu JL, Li SB, and Wang X analyzed the data and wrote the manuscript; and all authors have read and approve the final manuscript.
Supported byHebei Medical Science Research Project, No. 20191279.
Institutional review board statement: This study was approved by the institutional review board of Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine.
Informed consent statement: The study was a retrospective study and patients were not required to give informed consent to the study because the identified patient data was used from hospital database.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at hujl@sj-hospital.org.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Long Hu, PhD, Doctor, Department of Gastroenterology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110001, Liaoning Province, China. 360484590@qq.com
Received: November 10, 2023 Peer-review started: November 10, 2023 First decision: November 21, 2023 Revised: November 25, 2023 Accepted: December 6, 2023 Article in press: December 6, 2023 Published online: December 16, 2023 Processing time: 34 Days and 23.6 Hours
ARTICLE HIGHLIGHTS
Research background
Appendiceal mucinous neoplasms can present in a malignant fashion, but preoperative diagnosis of appendiceal mucinous neoplasms is difficult. Endoscopy plays an important role in the diagnosis of appendiceal mucinous neoplasms. There are limited reports regarding the endosonographic characteristics of these neoplasms.
Research motivation
We evaluated the imaging features of appendiceal mucinous neoplasms using endoscopic ultrasound (EUS) by curved linear-array echoendoscope.
Research objectives
To describe image features on endoscopic and echoendosonograhic views of appendiceal mucinous neoplasms.
Research methods
The EUS characteristics and patients’ clinical data were reviewed.
Research results
The appendiceal orifice located on the surface of the lesion in 2 cases (volcano sign) and the appendiceal orifice located on the surface of the lesion with white secretion in 2 cases (atypical volcano sign) were seen. EUS showed that the lesions were submucosal cystic hypoechoic lesions with clear boundaries and no wall nodules were observed. Onion-peeling sign, which was defined as intermittent hyperechoic lines in the hypoechoic lesion, could be observed in part of cases.
Research conclusions
This study demonstrated that we can safely evaluate the lesion in the ileocecal region by using a linear-array echoendoscope. A volcano sign on endoscopic view and EUS features could be used to diagnose appendiceal mucinous neoplasms.
Research perspectives
In the future, for difficult colonoscopy, the safety of intubation of linear echoendoscope into cecum should be studied.
