Zhang JC, Ma YY, Lan YZ, Li SB, Wang X, Hu JL. Evaluation of appendiceal mucinous neoplasms by curved linear-array echoendoscope: A preliminary study. World J Gastrointest Endosc 2023; 15(12): 699-704 [PMID: 38187914 DOI: 10.4253/wjge.v15.i12.699]
Corresponding Author of This Article
Jin-Long Hu, PhD, Doctor, Department of Gastroenterology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110001, Liaoning Province, China. 360484590@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jing-Chao Zhang, Yong-Zhen Lan, Xiao Wang, Endoscopy Center, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Yang-Yang Ma, Department of Gastrointestinal Surgery, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Shuang-Biao Li, Department of Pathology, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Jin-Long Hu, Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: Hu JL, Zhang JC, Ma YY, and Lan YZ designed and performed the research study; Hu JL, Li SB, and Wang X analyzed the data and wrote the manuscript; and all authors have read and approve the final manuscript.
Supported byHebei Medical Science Research Project, No. 20191279.
Institutional review board statement: This study was approved by the institutional review board of Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine.
Informed consent statement: The study was a retrospective study and patients were not required to give informed consent to the study because the identified patient data was used from hospital database.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at hujl@sj-hospital.org.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Long Hu, PhD, Doctor, Department of Gastroenterology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110001, Liaoning Province, China. 360484590@qq.com
Received: November 10, 2023 Peer-review started: November 10, 2023 First decision: November 21, 2023 Revised: November 25, 2023 Accepted: December 6, 2023 Article in press: December 6, 2023 Published online: December 16, 2023 Processing time: 34 Days and 23.6 Hours
Abstract
BACKGROUND
Preoperative diagnosis of appendiceal mucinous neoplasms is challenging, and there are few reports regarding the endosonographic characteristics of these neoplasms.
AIM
To provide a retrospective assessment of the imaging features of appendiceal mucinous neoplasms using endoscopic ultrasound (EUS) by curved linear-array echoendoscope.
METHODS
A database of all patients with appendiceal mucinous neoplasms who had received EUS examination at our hospital between January 2018 and July 2023 was retrospectively analyzed. The EUS characteristics and patients’ clinical data were reviewed.
RESULTS
Twenty-two patients were included in the study. The linear-array echoendoscope successfully reached the ileocecal region in every patient. In the endoscopic view, we could observe the protrusion in the appendiceal orifice in all patients. A volcano sign was observed in two patients, and an atypical volcano sign was seen in two patients. EUS showed that all 22 lesions were submucosal cystic hypoechoic lesions with clear boundaries. No wall nodules were observed, but an onion-peeling sign was observed in 17 cases.
CONCLUSION
Linear-array echoendoscope is safe to reach the ileocecal region under the guidance of EUS. Image features on endoscopic and echoendosonograhic views could be used to diagnose appendiceal mucinous neoplasms.
Core Tip: Appendiceal mucocele is a relatively rare disease. The preoperatively accurate diagnosis is crucial to the treatment strategy. Endoscopy has played an important role in the diagnosis of appendiceal mucocele. Image features on endoscopic and echoendosonograhic views could be used to diagnose appendiceal mucinous neoplasms.
