Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Dec 16, 2023; 15(12): 699-704
Published online Dec 16, 2023. doi: 10.4253/wjge.v15.i12.699
Evaluation of appendiceal mucinous neoplasms by curved linear-array echoendoscope: A preliminary study
Jing-Chao Zhang, Yang-Yang Ma, Yong-Zhen Lan, Shuang-Biao Li, Xiao Wang, Jin-Long Hu
Jing-Chao Zhang, Yong-Zhen Lan, Xiao Wang, Endoscopy Center, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Yang-Yang Ma, Department of Gastrointestinal Surgery, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Shuang-Biao Li, Department of Pathology, Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Cangzhou 061000, Hebei Province, China
Jin-Long Hu, Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: Hu JL, Zhang JC, Ma YY, and Lan YZ designed and performed the research study; Hu JL, Li SB, and Wang X analyzed the data and wrote the manuscript; and all authors have read and approve the final manuscript.
Supported by Hebei Medical Science Research Project, No. 20191279.
Institutional review board statement: This study was approved by the institutional review board of Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine.
Informed consent statement: The study was a retrospective study and patients were not required to give informed consent to the study because the identified patient data was used from hospital database.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at hujl@sj-hospital.org.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Long Hu, PhD, Doctor, Department of Gastroenterology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110001, Liaoning Province, China. 360484590@qq.com
Received: November 10, 2023
Peer-review started: November 10, 2023
First decision: November 21, 2023
Revised: November 25, 2023
Accepted: December 6, 2023
Article in press: December 6, 2023
Published online: December 16, 2023
Processing time: 34 Days and 23.6 Hours
Abstract
BACKGROUND

Preoperative diagnosis of appendiceal mucinous neoplasms is challenging, and there are few reports regarding the endosonographic characteristics of these neoplasms.

AIM

To provide a retrospective assessment of the imaging features of appendiceal mucinous neoplasms using endoscopic ultrasound (EUS) by curved linear-array echoendoscope.

METHODS

A database of all patients with appendiceal mucinous neoplasms who had received EUS examination at our hospital between January 2018 and July 2023 was retrospectively analyzed. The EUS characteristics and patients’ clinical data were reviewed.

RESULTS

Twenty-two patients were included in the study. The linear-array echoendoscope successfully reached the ileocecal region in every patient. In the endoscopic view, we could observe the protrusion in the appendiceal orifice in all patients. A volcano sign was observed in two patients, and an atypical volcano sign was seen in two patients. EUS showed that all 22 lesions were submucosal cystic hypoechoic lesions with clear boundaries. No wall nodules were observed, but an onion-peeling sign was observed in 17 cases.

CONCLUSION

Linear-array echoendoscope is safe to reach the ileocecal region under the guidance of EUS. Image features on endoscopic and echoendosonograhic views could be used to diagnose appendiceal mucinous neoplasms.

Keywords: Appendiceal mucinous neoplasm, Endoscopic ultrasound, Appendix, Endoscopy, Colonoscopy

Core Tip: Appendiceal mucocele is a relatively rare disease. The preoperatively accurate diagnosis is crucial to the treatment strategy. Endoscopy has played an important role in the diagnosis of appendiceal mucocele. Image features on endoscopic and echoendosonograhic views could be used to diagnose appendiceal mucinous neoplasms.