Published online Sep 16, 2025. doi: 10.4253/wjge.v17.i9.110170
Revised: July 9, 2025
Accepted: August 11, 2025
Published online: September 16, 2025
Processing time: 105 Days and 3.3 Hours
A recent study by Nishizawa et al presented significant findings regarding the advantages of next-generation colonoscopes, specifically the CF-XZ1200 and CF-EZ1500 models, in enhancing the adenoma and sessile serrated lesion detection rates. As colorectal cancer remains a leading cause of cancer-related mortality globally, the implications of improved detection rates are substantial. This letter advocated the adoption of advanced colonoscopy technology, emphasizing the robust methodology of the study, including propensity score matching, which enhanced the validity of its conclusions. Notable improvements in image quality, facilitated by innovations such as 4 K resolution and texture enhancement imaging, enable endoscopists to identify even the smallest lesions, ultimately leading to improved patient outcomes. Given the compelling evidence presented, it is imperative for healthcare institutions to prioritize the integration of these advanced scopes into routine practice to enhance screening efficacy and reduce the burden of colorectal cancer.
Core Tip: The adoption of next-generation colonoscopes represents a significant advancement in colorectal cancer screening. These advanced technologies enable the more precise detection of adenomas and sessile serrated lesions, improving patient outcomes and public health. Healthcare institutions should prioritize the integration of these technologies to enhance screening efficacy and potentially reduce colorectal cancer incidence and mortality. Investment in advanced colonoscopy equipment is aligned with broader initiatives to improve cancer prevention and early detection strategies. As the field of endoscopy continues to evolve, embracing these technological advancements is crucial for providing optimal patient care and advancing the fight against colorectal cancer.