Pre-transplant downstaging strategies for hepatocellular carcinoma with portal vein tumor thrombus: Current therapies and future challenges

doi:10.4254/wjh.v17.i11.110614

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Nov 27, 2025 (publication date) through Dec 5, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Nov 27, 2025; 17(11): 110614
Published online Nov 27, 2025. doi: 10.4254/wjh.v17.i11.110614

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Figure 1 Downstaging strategies for hepatocellular carcinoma with portal vein tumor thrombus. TACE: Transarterial chemoembolization; TARE: Transarterial radioembolization; PBT: Proton beam therapy; TKIS: Tyrosine kinase inhibitors; ICIS: Immune checkpoint inhibitors; IP-RFA: Intraportal radiofrequency ablation.

Citation: Li ZY, Xie C, Cai HQ. Pre-transplant downstaging strategies for hepatocellular carcinoma with portal vein tumor thrombus: Current therapies and future challenges. World J Hepatol 2025; 17(11): 110614
URL: https://www.wjgnet.com/1948-5182/full/v17/i11/110614.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i11.110614