Pathogenesis and research progress of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

Figure 1 Pathogenic factors and treatment of non-alcoholic steatohepatitis. NASH: Non-alcoholic steatohepatitis; SCFSs: Short-chain fatty acids; LPS: Lipopolysaccharide; TNF-α: Tumor Necrosis Factor-α; TLR4: Toll-like receptor 4; NF-κB: Nuclear factor kappa-B; GLP-1: Glucagon-like peptide-1; SGLT2i: Sodium-glucose cotransporter 2 inhibitors; PPAR α/β: Peroxisome proliferator-activated receptors α/β; FXR: Farnesoid X receptor; mAbs: Monoclonal antibodies.