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Letter to the Editor: Microplastics as promoters of metabolic dysfunction-associated steatotic liver disease: Mechanistic insights and implications
Nabil Eid, Department of Human Biology, School of Medicine, IMU University, Kuala Lumpur 57000, Malaysia
Author contributions: Eid N wrote, edited, and approved the final draft of the manuscript.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Corresponding author: Nabil Eid, Associate Professor, MD, PhD, Department of Human Biology, School of Medicine, IMU University, Bukit Jalil, Kuala Lumpur 57000, Malaysia. nabilsaleheid@imu.edu.my
Received: January 7, 2026
Revised: January 28, 2026
Accepted: March 6, 2026
Published online: June 27, 2026
Processing time: 164 Days and 4.7 Hours
Revised: January 28, 2026
Accepted: March 6, 2026
Published online: June 27, 2026
Processing time: 164 Days and 4.7 Hours
Core Tip
Core Tip: Metabolic dysfunction-associated steatotic liver disease is the most prevalent chronic liver disease worldwide and carries a risk of progression to hepatocellular carcinoma. Microplastics have emerged as environmental hazards and have been detected in human tissues, including the liver, brain, and blood. Recent preclinical evidence links microplastic exposure to metabolic dysfunction-associated steatotic liver disease through mechanisms involving metabolic stress, inflammation, and autophagy dysfunction, with potential clinical implications.