Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Hepatol. Mar 27, 2026; 18(3): 114435
Published online Mar 27, 2026. doi: 10.4254/wjh.v18.i3.114435
Published online Mar 27, 2026. doi: 10.4254/wjh.v18.i3.114435
Optimizing nutritional interventions in chronic liver disease: Etiology-specific strategies for enhanced clinical management
Mohamed Mahmoud Hafez, Faculty of Medicine, Helwan University, Cairo 11795, Egypt
Mark Nasseem, Internal Medicine, MedStar Washington Hospital Center, Washington, WA 20010, United States
Imane Boukhechem, Ahmed Tawheed, Department of Gastroenterology, Al Emadi Hospital, Doha 50000, Qatar
Reda ElSheikh, Department of Nutrition, Al Emadi Hospital, Doha 50000, Qatar
Author contributions: Tawheed A designed the overall concept and outline of the manuscript; Nasseem M wrote the manuscript; Boukhechem I revised the manuscript; ElSheikh R provided technical advice for revision. All authors have contributed to this article and have approved the final version of the manuscript.
Conflict-of-interest statement: No conflict of interest to be reported.
Corresponding author: Ahmed Tawheed, Consultant, Department of Gastroenterology, Al Emadi Hospital, D-Ring Road, Doha 50000, Qatar. atawheed1990@gmail.com
Received: September 19, 2025
Revised: November 20, 2025
Accepted: January 9, 2026
Published online: March 27, 2026
Processing time: 188 Days and 18.5 Hours
Revised: November 20, 2025
Accepted: January 9, 2026
Published online: March 27, 2026
Processing time: 188 Days and 18.5 Hours
Core Tip
Core Tip: Patients with chronic liver disease (CLD) may suffer from malnutrition, which may affect more than 90% of advanced CLD patients. The CLD review notes several mechanisms for nutritional deterioration including anorexia, malabsorption, and alterations of metabolism and outlines evidence-based, etiology-specific nutritional strategies. Inclusive of early assessment, multidisciplinary team care, individual-based intervention, nutritional management in CLD can greatly enhance patient outcomes and decrease disease burden.