Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. May 27, 2025; 17(5): 106892
Published online May 27, 2025. doi: 10.4254/wjh.v17.i5.106892
Transjugular intrahepatic portosystemic shunt creation using intravascular ultrasound vs fluoroscopic guidance: A dual-institution retrospective comparative study
Matthew L Hung, Abhishek Jairam, Matthew Carr, Zachary T Berman, Michael Taddonio, Jeet Minocha, Hamed Aryafar, Jeffrey I Mondschein, Michael C Soulen, Gregory J Nadolski, Jonas Redmond
Matthew L Hung, Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, United States
Abhishek Jairam, Zachary T Berman, Michael Taddonio, Jeet Minocha, Jonas Redmond, Department of Radiology, University of California San Diego Medical Center, San Diego, CA 92037, United States
Matthew Carr, Department of Radiology, University of California Los Angeles, Los Angeles, CA 90095, United States
Hamed Aryafar, Department of Radiology, Sharp Memorial Hospital, San Diego, CA 92123, United States
Jeffrey I Mondschein, Michael C Soulen, Gregory J Nadolski, Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, United States
Author contributions: Hung ML, Jairam A, and Carr M contributed to methodology, data curation and formal analysis; Hung ML, Berman ZT, Taddonio M, Minocha J, Aryafar H, Mondschein JI, Soulen MC, Nadolski GJ, and Redmond J contributed to the writing, reviewing and editing of the manuscript; Nadolski GJ, Redmond J were responsible for conceptualization of the project; and all authors thoroughly reviewed and endorsed the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Hospital of the University of Pennsylvania, approval No. 822828.
Informed consent statement: Informed consent was not required for this retrospective study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Data supporting the findings of this study are available upon request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Matthew L Hung, MD, Department of Radiology, Stanford University School of Medicine, 300 Pasteur Drive MC 5105, Stanford, CA 94305, United States. mlhung@stanford.edu
Received: March 11, 2025
Revised: April 8, 2025
Accepted: April 25, 2025
Published online: May 27, 2025
Processing time: 77 Days and 16.7 Hours
Core Tip

Core Tip: A comparison of intravascular ultrasound vs fluoroscopic guidance in the creation of a transjugular intrahepatic portosystemic shunt demonstrates that imaging guidance modality has no impact on shunt patency or mortality in intermediate-term follow-up, or liver injury at 1 month. However, the use of intravascular ultrasound decreases radiation exposure and procedure time compared to fluoroscopic guidance. Imaging guidance modality therefore affects procedural metrics, but does not appear to impact subsequent clinical outcomes.