Editorial
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. May 27, 2025; 17(5): 104468
Published online May 27, 2025. doi: 10.4254/wjh.v17.i5.104468
Infection risk and management in patients with cirrhosis: A critical overview
Miguel Suárez, Raquel Martínez, Raquel Gómez-Molina, Jorge Mateo
Miguel Suárez, Raquel Martínez, Department of Gastroenterology, Virgen de la Luz Hospital, Cuenca 16002, Castille-La Mancha, Spain
Miguel Suárez, Raquel Martínez, Jorge Mateo, Medical Analysis Expert Group, Institute of Technology, Universidad de Castilla-La Mancha, Cuenca 16071, Castille-La Mancha, Spain
Miguel Suárez, Raquel Martínez, Jorge Mateo, Medical Analysis Expert Group, Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Toledo 45071, Castille-La Mancha, Spain
Raquel Gómez-Molina, Department of Laboratory Medicine, Virgen de la Luz Hospital, Cuenca 16002, Castille-La Mancha, Spain
Co-first authors: Miguel Suárez and Raquel Martínez.
Author contributions: Suárez M, Martínez R, and Mateo J participated in the design and structure of the manuscript; Suárez M, Martínez R, and Gómez-Molina contributed to the review of the literature, writing and the elaboration of the table; All authors have reviewed the paper. Suárez M and Martínez R contributed equally as co-first authors.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Miguel Suárez, MD, PhD, Associate Chief Physician, Department of Gastroenterology, Virgen de la Luz Hospital, 1 Hermandad Donantes De Sangre, Cuenca 16002, Castille-La Mancha, Spain. msuarezmatias@sescam.jccm.es
Received: December 23, 2024
Revised: February 27, 2025
Accepted: March 13, 2025
Published online: May 27, 2025
Processing time: 156 Days and 13.2 Hours
Core Tip

Core Tip: Patients with cirrhosis face a significantly higher risk of infections, which often trigger acute decompensations and worsen their prognosis. The study by El Labban et al emphasizes the need for early detection and understanding of the complex pathophysiology of patients with cirrhosis, including immune dysfunction, intestinal permeability, and the risk of multidrug-resistant organisms. Recognizing these factors and adopting multidisciplinary, patient-tailored approaches are critical to mitigating the heightened morbidity and mortality observed in this population.