Observational Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Mar 27, 2025; 17(3): 103537
Published online Mar 27, 2025. doi: 10.4254/wjh.v17.i3.103537
Patterns of dietary supplement use among United States patients with steatotic liver disease: Vitamins, minerals and botanicals
Melinda Wang, Gabrielle Jutras, Giuseppe Cullaro, Anand Dhruva, Jennifer C Lai
Melinda Wang, Department of Internal Medicine, University of California San Francisco, San Francisco, CA 94143, United States
Gabrielle Jutras, Division of Hepatology, Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montreal H2X 0A9, Quebec, Canada
Giuseppe Cullaro, Jennifer C Lai, Department of Medicine, Division of Gastroenterology and Hepatology, University of California – San Francisco, San Francisco, CA 94143, United States
Anand Dhruva, Osher Center for Integrative Medicine, University of California, California, MD 94143, United States
Co-first authors: Melinda Wang and Gabrielle Jutras.
Author contributions: Wang M and Jutras G contributed to study conception, study design, statistical analysis, manuscript writing and editing; Cullaro G contributed to manuscript editing, funding; Dhruva A contributed to study design, manuscript editing.
Supported by The National Institutes of Health, No. K24AG080021, No. R01AG059183, and No. P30DK026743.
Institutional review board statement: Written informed consent is obtained from all participants or proxies and NHANES survey protocol is approved by the Research Ethics Review Board at the Centers for Disease Control and Prevention, National Center for Health Statistics.
Informed consent statement: Written informed consent is obtained from all participants or proxies and NHANES survey protocol is approved by the Research Ethics Review Board at the Centers for Disease Control and Prevention, National Center for Health Statistics.
Conflict-of-interest statement: Lai: Nestle Nutrition Sciences (unrestricted educational grant); Novo Nordisk (advisory board; consultant); Genfit (consultant); Boehringer Ingelheim (advisory board).
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement- checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jennifer C Lai, Department of Medicine, Division of Gastroenterology and Hepatology, University of California-San Francisco, 513 Parnassus Avenue, UCSF Box 0538, San Francisco, CA 94143, United States. jennifer.lai@ucsf.edu
Received: November 22, 2024
Revised: December 26, 2024
Accepted: January 27, 2025
Published online: March 27, 2025
Processing time: 124 Days and 7.8 Hours
Core Tip

Core Tip: Almost half of patients with steatotic liver disease (SLD) report taking dietary supplements (DS). Older patients, women, and patients with higher education/food security are more likely to use DS. Patients with SLD take DS to improve their health and by doctor’s advice. Hepatologists have an opportunity to address DS use during clinic visits.