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Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Oct 27, 2025; 17(10): 109583
Published online Oct 27, 2025. doi: 10.4254/wjh.v17.i10.109583
Novel educational video module about alcohol use disorder increases treatment rates and decreases return to alcohol use
Patrick Twohig, Zachary P Slocum, Anna Willet, Makayla Schissel, Alëna A Balasanova, Kyle Scholten, Josh Warner, Tomoki Sempokuya, Nathalie Khoury, Allison Ashford, Thoetchai B Peeraphatdit
Patrick Twohig, Department of Gastroenterology and Hepatology, University of Rochester Medical Center, Rochester, NY 14682, United States
Zachary P Slocum, Kyle Scholten, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, United States
Anna Willet, Department of Transplant Hepatology, Sanford Health, Sioux Falls, SD 57105, United States
Makayla Schissel, Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE 68198, United States
Alëna A Balasanova, Department of Psychiatry, University of Nebraska Medical Center, Omaha, NE 68198, United States
Josh Warner, Department of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE 68198, United States
Tomoki Sempokuya, Division of Gastroenterology and Hepatology, Department of Medicine, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, United States
Nathalie Khoury, Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, United States
Allison Ashford, Department of Medicine and Pediatrics, University of Nebraska Medical Center, Omaha, NE 68198, United States
Thoetchai B Peeraphatdit, Department of Gastroenterology and Hepatology, Midwest Gastrointestinal Associates, Omaha, NE 68114, United States
Author contributions: Twohig P and Peeraphatdit TB designed the overall concept and outline of the project and manuscript; Twohig P, Willet A, Scholten K, Warner J, and Sempokuya T performed patient recruitment; Schissel M performed data analysis; Balasanova AA, Khoury N, and Ashford A provided critical revisions of the manuscript and assisted with study design; and all authors assisted with drafting and revising the manuscript and approved the submitted version.
Institutional review board statement: This study was approved by the Medical Ethics Committee of University of Nebraska Medical Center, approval No. #0342-22-EP.
Informed consent statement: All involved persons (subjects or legally authorized representative) gave their informed consent (both written and verbal) prior to study inclusion.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Dataset and statistical code available from the corresponding author. Participants gave informed consent for data sharing.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Patrick Twohig, MD, FRCPC, Assistant Professor, Department of Gastroenterology and Hepatology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14682, United States. patrick_twohig@urmc.rochester.edu
Received: May 16, 2025
Revised: May 30, 2025
Accepted: September 11, 2025
Published online: October 27, 2025
Processing time: 165 Days and 8.5 Hours
Core Tip

Core Tip: This prospective single-center study evaluated the impact of an educational video module (EVM) on promoting alcohol use disorder treatment among hospitalized patients with alcohol-associated liver disease. The study included 42 patients and compared outcomes with a retrospective control group. Viewing the EVM significantly increased rates of pharmacologic (50% vs 22%) and psychosocial treatment (73.8% vs 44%) within 30 days of discharge. Return to alcohol use was also significantly reduced (7.9% vs 35.6%). All participants endorsed the EVM. The findings suggest EVMs can effectively bridge knowledge gaps and improve treatment engagement for patients with alcohol-associated liver disease and alcohol use disorder.