Novel educational video module about alcohol use disorder increases treatment rates and decreases return to alcohol use

doi:10.4254/wjh.v17.i10.109583

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Oct 27, 2025; 17(10): 109583
Published online Oct 27, 2025. doi: 10.4254/wjh.v17.i10.109583

Novel educational video module about alcohol use disorder increases treatment rates and decreases return to alcohol use

Patrick Twohig, Zachary P Slocum, Anna Willet, Makayla Schissel, Alëna A Balasanova, Kyle Scholten, Josh Warner, Tomoki Sempokuya, Nathalie Khoury, Allison Ashford, Thoetchai B Peeraphatdit

Patrick Twohig, Department of Gastroenterology and Hepatology, University of Rochester Medical Center, Rochester, NY 14682, United States

Zachary P Slocum, Kyle Scholten, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, United States

Anna Willet, Department of Transplant Hepatology, Sanford Health, Sioux Falls, SD 57105, United States

Makayla Schissel, Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE 68198, United States

Alëna A Balasanova, Department of Psychiatry, University of Nebraska Medical Center, Omaha, NE 68198, United States

Josh Warner, Department of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE 68198, United States

Tomoki Sempokuya, Division of Gastroenterology and Hepatology, Department of Medicine, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, United States

Nathalie Khoury, Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, United States

Allison Ashford, Department of Medicine and Pediatrics, University of Nebraska Medical Center, Omaha, NE 68198, United States

Thoetchai B Peeraphatdit, Department of Gastroenterology and Hepatology, Midwest Gastrointestinal Associates, Omaha, NE 68114, United States

Author contributions: Twohig P and Peeraphatdit TB designed the overall concept and outline of the project and manuscript; Twohig P, Willet A, Scholten K, Warner J, and Sempokuya T performed patient recruitment; Schissel M performed data analysis; Balasanova AA, Khoury N, and Ashford A provided critical revisions of the manuscript and assisted with study design; and all authors assisted with drafting and revising the manuscript and approved the submitted version.

Institutional review board statement: This study was approved by the Medical Ethics Committee of University of Nebraska Medical Center, approval No. #0342-22-EP.

Informed consent statement: All involved persons (subjects or legally authorized representative) gave their informed consent (both written and verbal) prior to study inclusion.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.

Data sharing statement: Dataset and statistical code available from the corresponding author. Participants gave informed consent for data sharing.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Patrick Twohig, MD, FRCPC, Assistant Professor, Department of Gastroenterology and Hepatology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14682, United States. patrick_twohig@urmc.rochester.edu

Received: May 16, 2025
Revised: May 30, 2025
Accepted: September 11, 2025
Published online: October 27, 2025
Processing time: 165 Days and 6.3 Hours

Abstract

BACKGROUND

Patients and providers are often unaware of available treatment options for alcohol use disorder (AUD) and how to pursue them.

AIM

To improve AUD treatment rates using an educational video module (EVM).

METHODS

Prospective single-center cohort study evaluating the impact of a novel interactive patient EVM in promoting AUD treatment among hospitalized patients with alcohol-associated liver disease. Treatment was defined as receiving medication or participating in psychosocial treatment within 30 days of discharge. Primary outcome was change in treatment rates after viewing the EVM compared to a retrospective control cohort. Secondary outcomes were predictors of receiving treatment, EVM feedback, 30-day hospital readmission, outpatient follow-up, return to alcohol use, and mortality.

RESULTS

Forty-two patients were included. Mean age was 45 years, 50% were female, and mean model for end-stage liver disease score 15.5. After viewing the EVM, treatment rates increased for pharmacologic (50% vs 22%, P = 0.0008) and psychosocial treatment (73.8% vs 44%, P = 0.01). Return to alcohol use was significantly lower (7.9% vs 35.6%, P = 0.003). All 100% of patients would recommend the EVM.

CONCLUSION

EVM allows hospitalized patients to receive standardized education about AUD treatment. This may address patient and provider knowledge gaps and reduce the growing burden of alcohol-associated liver disease. Future studies should evaluate EVM in larger patient populations using a multi-center study design.

Keywords: Alcohol use disorder; Addiction treatment; Alcohol-associated liver disease; Quality improvement; Patient education; Video; Hospital-based intervention

Core Tip: This prospective single-center study evaluated the impact of an educational video module (EVM) on promoting alcohol use disorder treatment among hospitalized patients with alcohol-associated liver disease. The study included 42 patients and compared outcomes with a retrospective control group. Viewing the EVM significantly increased rates of pharmacologic (50% vs 22%) and psychosocial treatment (73.8% vs 44%) within 30 days of discharge. Return to alcohol use was also significantly reduced (7.9% vs 35.6%). All participants endorsed the EVM. The findings suggest EVMs can effectively bridge knowledge gaps and improve treatment engagement for patients with alcohol-associated liver disease and alcohol use disorder.