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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Oct 27, 2025; 17(10): 109092
Published online Oct 27, 2025. doi: 10.4254/wjh.v17.i10.109092
Published online Oct 27, 2025. doi: 10.4254/wjh.v17.i10.109092
Evolution of hepatology practice in Mexico and Latin America: From biochemical markers to genomic medicine
Arturo Panduro, Sonia Roman, Leonardo Leal-Mercado, Juan P Cardenas-Benitez, Irene M Mariscal-Martinez, Department of Genomic Medicine in Hepatology, Civil Hospital of Guadalajara, Fray Antonio Alcalde, Guadalajara 44280, Jalisco, Mexico
Arturo Panduro, Sonia Roman, Leonardo Leal-Mercado, Juan P Cardenas-Benitez, Irene M Mariscal-Martinez, Health Sciences Center, University of Guadalajara, Guadalajara 44340, Jalisco, Mexico
Co-first authors: Arturo Panduro and Sonia Roman.
Author contributions: Panduro A and Roman S conceptualized and drafted the manuscript; Panduro A and Roman S contributed equally to this article, they are the co-first authors of this manuscript; Panduro A, Roman S, Leal-Mercado L, Cardenas-Benitez JP, and Mariscal-Martinez IM conducted the investigation and wrote, edited, and contributed intellectually to this manuscript; and all authors revised and approved the final manuscript.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Arturo Panduro, MD, PhD, FAASLD, Department of Genomic Medicine in Hepatology, Civil Hospital of Guadalajara, Fray Antonio Alcalde, Hospital #278, Col. El Retiro, Guadalajara 44280, Jalisco, Mexico. apanduro53@gmail.com
Received: April 30, 2025
Revised: June 4, 2025
Accepted: September 22, 2025
Published online: October 27, 2025
Processing time: 181 Days and 9.1 Hours
Revised: June 4, 2025
Accepted: September 22, 2025
Published online: October 27, 2025
Processing time: 181 Days and 9.1 Hours
Core Tip
Core Tip: Genomic medicine in hepatology studies the gene-environment interactions that lead to the development of liver diseases. The liver expresses numerous genes involved in the physiology and pathophysiology of several comorbidities, such as diabetes, chronic liver disease, and cardiovascular disease. This work aimed to provide an overview of the study of the liver from its early days to genomic medicine, emphasizing its role in chronic diseases and its use in diagnosing and preventing them at early stages. It also highlighted the need to train healthcare professionals in genomic medicine, creating a new approach to medicine in Mexico and other Latin American countries.