Randomized Controlled Trial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Dec 27, 2024; 16(12): 1458-1467
Published online Dec 27, 2024. doi: 10.4254/wjh.v16.i12.1458
Effects of nocturnal snacks on body composition in patients with liver cirrhosis
Yong-Bo Yu, Xiu-Juan Fu, Guo-Fen Xu, Ling-Yun Niu, Ruo-Nan Duan, Jia Yao, Ning-Hui Zhao
Yong-Bo Yu, Department of Neurology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan 030032, Shanxi Province, China
Xiu-Juan Fu, Guo-Fen Xu, Ling-Yun Niu, Jia Yao, Ning-Hui Zhao, Department of Gastroenterology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan 030032, Shanxi Province, China
Ruo-Nan Duan, Department of Nutrition, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan 030032, Shanxi Province, China
Author contributions: Yu YB and Zhao NH wrote the manuscript; Fu XJ and Xu GF collected the data; Niu LY and Duan RN analyzed and interpreted the data; Zhao NH and Yao J provided financial support; Yao J made critical revisions; All authors read and approved the final manuscript.
Supported by the Fundamental Research Program of Shanxi Province, No. 202103021224341 and No. 202203021222342; Science and Technology Cooperation and Exchange Special Project of Shanxi Province, No. 202304041101048; and Science Foundation of Shanxi Bethune Hospital, No. 2023YJ07.
Institutional review board statement: The study was reviewed and approved by Ethics Committee of Shanxi Medical University, No. 2021GLL154.
Clinical trial registration statement: This study is under registration at http://www.chictr.org.cn.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors declare that there is no conflict of interests in this study.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ning-Hui Zhao, MD, Attending Doctor, Department of Gastroenterology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, No. 99 Longcheng Street, Taiyuan 030032, Shanxi Province, China. znh7525@163.com
Received: July 6, 2024
Revised: August 10, 2024
Accepted: August 19, 2024
Published online: December 27, 2024
Processing time: 145 Days and 22.5 Hours
Core Tip

Core Tip: This randomized controlled study compared the effects of nocturnal snacks in patients with liver cirrhosis. The body composition of 70 cirrhotic patients, including the normal diet group and the nocturnal snacks group, and 30 healthy controls, were detected using the InBody 720 body composition analyzer. The results showed that the long-term nocturnal snacks may improve body composition indices such as body fat mass, visceral fat area and body cell mass to some extent in patients with cirrhosis.