©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Dec 27, 2023; 15(12): 1333-1337
Published online Dec 27, 2023. doi: 10.4254/wjh.v15.i12.1333
Published online Dec 27, 2023. doi: 10.4254/wjh.v15.i12.1333
Drug induced autoimmune hepatitis: An unfortunate case of herbal toxicity from Skullcap supplement: A case report
Nimish Thakral, Venkata Rajesh Konjeti, Fady William Salama, Department of Digestive Diseases and Nutrition, University of Kentucky, Lexington, KY 40536, United States
Author contributions: Thakral N, Konjeti VR, and Salama F were involved in patient care and drafting of the manuscript.
Informed consent statement: Our institution does not require separate consent for case reports.
Conflict-of-interest statement: There are no conflicts of interest associated with our report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Nimish Thakral, MBBS, MD, Assistant Professor, Department of Digestive Diseases and Nutrition, University of Kentucky, 800 Rose St., Lexington, KY 40536, United States. thakral.nimish@uky.edu
Received: July 16, 2023
Peer-review started: July 16, 2023
First decision: August 14, 2023
Revised: September 14, 2023
Accepted: November 24, 2023
Article in press: November 24, 2023
Published online: December 27, 2023
Processing time: 161 Days and 9.7 Hours
Peer-review started: July 16, 2023
First decision: August 14, 2023
Revised: September 14, 2023
Accepted: November 24, 2023
Article in press: November 24, 2023
Published online: December 27, 2023
Processing time: 161 Days and 9.7 Hours
Core Tip
Core Tip: This case report highlights a rare presentation of drug induced liver injury from Skullcap supplement usage. While Chinese Skullcap (Scutellaria baicalensis) has been associated with a mixed hepatocellular and cholestatic picture of drug-induced liver injuries, the association of North American Skullcap is not as robust. Here we present a case of drug induced autoimmune hepatitis from North American Skullcap supplement use. Hepatologists must be aware of this association of rare histopathological presentation.