Qiu XX, Li Z. Bioactive constituents and action mechanism of Xiaoyao San for treatment of non-alcoholic fatty liver disease. World J Hepatol 2024; 16(10): 1213-1215 [PMID: 39474580 DOI: 10.4254/wjh.v16.i10.1213]
Corresponding Author of This Article
Zheng Li, PhD, Lecturer, Pharmacist, Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou 221000, Jiangsu Province, China. lizhengcpu@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Oct 27, 2024; 16(10): 1213-1215 Published online Oct 27, 2024. doi: 10.4254/wjh.v16.i10.1213
Bioactive constituents and action mechanism of Xiaoyao San for treatment of non-alcoholic fatty liver disease
Xiao-Xia Qiu, Zheng Li
Xiao-Xia Qiu, Department of Research and Education, Shulan (Hangzhou) Hospital, Affiliated to Zhejiang Shuren University Shulan International Medical College, Hangzhou 310022, Zhejiang Province, China
Zheng Li, Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221000, Jiangsu Province, China
Author contributions: Li Z designed the article; Qiu XX and Li Z drafted and revised the article.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zheng Li, PhD, Lecturer, Pharmacist, Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou 221000, Jiangsu Province, China. lizhengcpu@163.com
Received: August 5, 2024 Revised: September 24, 2024 Accepted: October 9, 2024 Published online: October 27, 2024 Processing time: 77 Days and 0.7 Hours
Abstract
Xiaoyao San (XYS) is a classic Chinese medicine prescription. It is traditionally used to relieve syndrome of “liver stagnation and spleen deficiency”, a common syndrome type in traditional Chinese medicine, through soothing liver, tonifying spleen, and nourishing blood. Correspondingly, XYS has long application in the treatment of depression, dyspepsia and liver diseases. Given the rising of cutting-edge researches on XYS, there’s a significant need to diligently uncover the bioactive constituents and action mechanisms of XYS for treating non-alcoholic fatty liver disease accordingly.
Core Tip: Xiaoyao San (XYS) is a classic Chinese medicine prescription. It consists of 8 kinds of herbs, which thus contains abundant bioactive constituents to exert various biological effects. XYS has functions on relief of “liver stagnation and spleen deficiency”, and has long been used to treat liver diseases. Extensive effort has been made in the investigation of effective substances and action mechanisms of XYS against non-alcoholic fatty liver disease, and these achievements could contribute to build up the scientific foundation for its clinical application.
