Published online May 27, 2023. doi: 10.4254/wjh.v15.i5.666
Peer-review started: January 17, 2023
First decision: February 21, 2023
Revised: February 27, 2023
Accepted: April 18, 2023
Article in press: April 18, 2023
Published online: May 27, 2023
Processing time: 126 Days and 16.1 Hours
Celiac disease (CD) is a chronic inflammatory intestinal disorder mediated by the ingestion of gluten in genetically susceptible individuals. Liver involvement in CD has been widely described, and active screening for CD is recommended in patients with liver diseases, particularly in those with autoimmune disorders, fatty liver in the absence of metabolic syndrome, noncirrhotic intrahepatic portal hypertension, cryptogenic cirrhosis, and in the context of liver transplantation. Non-alcoholic fatty liver disease is estimated to affect approximately 25% of the world’s adult population and is the world’s leading cause of chronic liver disease. In view of both diseases’ global significance, and to their correlation, this study reviews the available literature on fatty liver and CD and verifies particularities of the clinical setting.
Core Tip: In view of fatty liver and celiac disease (CD) global significance, and to their correlation, this study reviews the available literature on fatty liver and CD and verifies particularities of the clinical setting.