Human pluripotent stem cells: Towards therapeutic development for the treatment of lifestyle diseases

doi:10.4252/wjsc.v8.i2.56

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Feb 26, 2016 (publication date) through Nov 1, 2025

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Feb 26, 2016; 8(2): 56-61
Published online Feb 26, 2016. doi: 10.4252/wjsc.v8.i2.56

Table 1 Clinical application of human pluripotent stem cells

Human pluripotent stem cells	Sources	Ethical hurdle	Safety
ESCs	Embryos	High	Relatively high¹
Allogenic iPSCs (with immunosuppression)	Cell banks	Low	Not yet evaluated
Allogenic iPSCs (without immunosuppression)		Low	High
Autologous iPSCs	Patient samples	Low	Under evaluation

Advantages and disadvantages of each kind of human pluripotent stem cells are described.

¹Up till now, no severe side effects have been reported. ESCs: Embryonic stem cells; iPSCs: Induced pluripotent stem cells.

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Citation: Nishio M, Nakahara M, Yuo A, Saeki K. Human pluripotent stem cells: Towards therapeutic development for the treatment of lifestyle diseases. World J Stem Cells 2016; 8(2): 56-61
URL: https://www.wjgnet.com/1948-0210/full/v8/i2/56.htm
DOI: https://dx.doi.org/10.4252/wjsc.v8.i2.56