Adipose tissue as a living drug: Stromal vascular fraction and adipose tissue-derived stem cells in regenerative medicine

Figure 1 Historical background of adipose tissue use in therapy. SVF: Stromal vascular fraction; ASCs: Adipose-derived stem cells.

Figure 2 Clinical applications and translational insights of stromal vascular fraction and adipose-derived stem cells. SVF: Stromal vascular fraction; ASCs: Adipose-derived stem cells.

Figure 3 Adipose tissue as a living drug: Stromal vascular fraction and adipose-derived stem cells in regenerative medicine. SVF: Stromal vascular fraction; ASCs: Adipose-derived stem cells; mSVF: Mechanical isolation of stromal vascular fraction; eSVF: Enzymatic isolation of stromal vascular fraction; IL: Interleukin; TNF: Tumor necrosis factor; SDF-1: Stromal-derived factor-1; CXCL12: C-X-C motif ligand 12; CCL2: C-C motif ligand 2; MCP-1: Monocyte chemoattractant protein-1; VEGF: Vascular endothelial growth factor; HGF: Hepatocyte growth factor; IGF-1: Insulin-like growth factor 1; FGF-2: Fibroblast growth factor-2; PDGF: Platelet-derived growth factor; TGF: Transforming growth factor; BMP-2: Bone morphogenetic protein-2; PGE2: Prostaglandin E2; IDO: Indoleamine 2,3-dioxygenase; MMPs: Matrix metalloproteinases; TIMPs: Tissue inhibitors of metalloproteinases.