Orchestrating stem cell fate: Novel tools for regenerative medicine

doi:10.4252/wjsc.v11.i8.464

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Aug 26, 2019 (publication date) through Nov 24, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Aug 26, 2019; 11(8): 464-475
Published online Aug 26, 2019. doi: 10.4252/wjsc.v11.i8.464

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Figure 1 Epigenetic regulation of stem cell fate. Chromatin remodeling affects cell behavior and regulates the balance between pluripotency and differentiation. HDACs: Histone deacetylases; Oct-4: Octamer-binding transcription factor 4; Sox-2: Sex determining region Y-box 2; NANOG: Nanog homeobox.

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Figure 2 Natural molecules and stem cell fate. Bioactive molecules induce cell proliferation and differentiation, reducing ROS production and apoptosis, through chromatin remodeling and epigenetic modifications. ROS: Reactive oxygen species; HDACs: Histone deacetylases.

Citation: Cruciani S, Santaniello S, Montella A, Ventura C, Maioli M. Orchestrating stem cell fate: Novel tools for regenerative medicine. World J Stem Cells 2019; 11(8): 464-475
URL: https://www.wjgnet.com/1948-0210/full/v11/i8/464.htm
DOI: https://dx.doi.org/10.4252/wjsc.v11.i8.464