©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Feb 26, 2016; 8(2): 22-31
Published online Feb 26, 2016. doi: 10.4252/wjsc.v8.i2.22
Published online Feb 26, 2016. doi: 10.4252/wjsc.v8.i2.22
Insights into kidney stem cell development and regeneration using zebrafish
Bridgette E Drummond, Rebecca A Wingert, Department of Biological Sciences, Center for Zebrafish Research, Center for Stem Cells and Regenerative Medicine, University of Notre Dame, Notre Dame, IN 46556, United States
Author contributions: Drummond BE and Wingert RA conceived, drafted and revised the paper.
Supported by National Institutes of Health, No. DP2 OD008470; Private funding was provided from the University of Notre Dame College of Science and Graduate School, as well as a generous donation to support stem cell research provided by the Gallagher Family.
Conflict-of-interest statement: Authors declare no conflict of interest for this article.
Correspondence to: Rebecca A Wingert, PhD, Department of Biological Sciences, Center for Zebrafish Research, Center for Stem Cells and Regenerative Medicine, University of Notre Dame, 100 Galvin Life Sciences, Notre Dame, IN 46556, United States. rwingert@nd.edu
Telephone: +1-574-6310907 Fax: +1-574-6317413
Received: August 29, 2015
Peer-review started: September 6, 2015
First decision: November 27, 2015
Revised: December 17, 2015
Accepted: January 8, 2016
Article in press: January 11, 2016
Published online: February 26, 2016
Processing time: 178 Days and 9.2 Hours
Peer-review started: September 6, 2015
First decision: November 27, 2015
Revised: December 17, 2015
Accepted: January 8, 2016
Article in press: January 11, 2016
Published online: February 26, 2016
Processing time: 178 Days and 9.2 Hours
Core Tip
Core tip: The emergence of regeneration-based options for kidney disease has the potential to reduce the growing worldwide health burden of these heterogenous conditions. Research into the mechanisms of renal regeneration in vertebrates like the zebrafish may provide knowledge about fundamental principles that could be useful for cellular reprogramming or endogenous modulation of kidney cells in humans.