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World J Stem Cells. Sep 26, 2021; 13(9): 1278-1292
Published online Sep 26, 2021. doi: 10.4252/wjsc.v13.i9.1278
Neural stem cell therapy for brain disease
Lan Zhao, Jian-Wei Liu, Hui-Yan Shi, Ya-Min Ma
Lan Zhao, Hui-Yan Shi, Ya-Min Ma, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
Lan Zhao, Hui-Yan Shi, Ya-Min Ma, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China
Jian-Wei Liu, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Author contributions: Zhao L wrote the paper and was responsible for the research funding; Liu JW and Shi HY were involved in the data collection; Ma YM was responsible for the review revision; All authors approved the final version of the manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lan Zhao, PhD, Research Fellow, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 88 Chang Ling Road, Xi Qing District, Tianjin 300381, China. lanzhao69@163.com
Received: February 27, 2021
Peer-review started: February 27, 2021
First decision: May 5, 2021
Revised: May 28, 2021
Accepted: August 27, 2021
Article in press: August 27, 2021
Published online: September 26, 2021
Processing time: 202 Days and 23.8 Hours
Core Tip

Core Tip: In this review, we elaborate on the characteristics of neural stem cells (NSCs) and their effects on the treatment of traumatic brain injury, hypoxic-ischemic brain injury, Alzheimer’s disease and Parkinson’s disease. At the same time, we discuss the applications and limitations of NSCs to treat brain diseases.