©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Jan 26, 2019; 11(1): 1-12
Published online Jan 26, 2019. doi: 10.4252/wjsc.v11.i1.1
Published online Jan 26, 2019. doi: 10.4252/wjsc.v11.i1.1
Human adult pluripotency: Facts and questions
Luminita Labusca, National Institute of Research and Development for Advanced Technical Physics Iasi, Iasi 700349, Romania
Kaveh Mashayekhi, Systems Biomedical Informatics and Modeling, Frankfurt D-45367, Germany
Author contributions: Labusca L conceived the manuscript and collected supportive literature; Mashayekhi K designed the bioinformatics input and revised the presented data and information.
Conflict-of-interest statement: All authors have no conflicts of interest to report.
Corresponding author: Luminita Labusca, MD, PhD, Chief Doctor, Senior Researcher, Senior Scientist, Surgeon, National Institute of Research and Development for Advanced Technical Physics Iasi, 47 Mangeron Boulevard, Iasi 700349, Romania. llabusca@phys-iasi.ro
Telephone: +40-74-9162219
Received: October 13, 2018
Peer-review started: October 15, 2018
First decision: November 1, 2018
Revised: November 6, 2018
Accepted: January 10, 2019
Article in press: January 10, 2019
Published online: January 26, 2019
Processing time: 104 Days and 21.7 Hours
Peer-review started: October 15, 2018
First decision: November 1, 2018
Revised: November 6, 2018
Accepted: January 10, 2019
Article in press: January 10, 2019
Published online: January 26, 2019
Processing time: 104 Days and 21.7 Hours
Core Tip
Core tip: Several types of human adult pluripotent stem cells have been described. Their origin and role remain largely unknown. The elucidation of possible stress-induced pluripotency phenomena could enable regenerative as well as tumour-suppressive therapies.