Grawish ME. Gingival-derived mesenchymal stem cells: An endless resource for regenerative dentistry. World J Stem Cells 2018; 10(9): 116-118 [PMID: 30310530 DOI: 10.4252/wjsc.v10.i9.116]
Corresponding Author of This Article
Mohammed E Grawish, PhD, Professor, Department of Oral Biology, Faculty of Dentistry, Mansoura University, Mansoura 740005, Egypt. grawish2004@mans.edu.eg
Research Domain of This Article
Dentistry, Oral Surgery & Medicine
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Stem Cells. Sep 26, 2018; 10(9): 116-118 Published online Sep 26, 2018. doi: 10.4252/wjsc.v10.i9.116
Gingival-derived mesenchymal stem cells: An endless resource for regenerative dentistry
Mohammed E Grawish
Mohammed E Grawish, Department of Oral Biology, Faculty of Dentistry, Mansoura University, Mansoura 740005, Egypt
Author contributions: Grawish ME wrote this editorial.
Conflict-of-interest statement: The author has no conflict of interest to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Mohammed E Grawish, PhD, Professor, Department of Oral Biology, Faculty of Dentistry, Mansoura University, Mansoura 740005, Egypt. grawish2004@mans.edu.eg
Telephone: +20-122-7971677
Received: May 14, 2018 Peer-review started: May 14, 2018 First decision: June 6, 2018 Revised: June 8, 2018 Accepted: June 30, 2018 Article in press: June 30, 2018 Published online: September 26, 2018 Processing time: 135 Days and 14.7 Hours
Core Tip
Core tip: Current therapeutic interventions in dentistry depend on biomaterials such as metals, polymers, ceramics, and composites. These restorative synthetic dental materials cannot restore the physiological architecture and function of the tissue. Thus, dentistry should move from restorative to regenerative dentistry, with the ability to regrow damaged or missing teeth with their own dental stem cells. Regenerating an entire tooth or individual parts of the tooth require a suitable number of specific stem cell populations for use and implantation. Considering their neural crest origin and ease of availability, gingival-derived mesenchymal stem cells should be considered as an attractive source for stem cells that can be used in regenerative dentistry.
