Gingival-derived mesenchymal stem cells: An endless resource for regenerative dentistry

doi:10.4252/wjsc.v10.i9.116

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World Journal of Stem Cells

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Editorial

World J Stem Cells. Sep 26, 2018; 10(9): 116-118
Published online Sep 26, 2018. doi: 10.4252/wjsc.v10.i9.116

Gingival-derived mesenchymal stem cells: An endless resource for regenerative dentistry

Mohammed E Grawish

Mohammed E Grawish, Department of Oral Biology, Faculty of Dentistry, Mansoura University, Mansoura 740005, Egypt

Author contributions: Grawish ME wrote this editorial.

Conflict-of-interest statement: The author has no conflict of interest to declare.

Correspondence to: Mohammed E Grawish, PhD, Professor, Department of Oral Biology, Faculty of Dentistry, Mansoura University, Mansoura 740005, Egypt. grawish2004@mans.edu.eg

Telephone: +20-122-7971677

Received: May 14, 2018
Peer-review started: May 14, 2018
First decision: June 6, 2018
Revised: June 8, 2018
Accepted: June 30, 2018
Article in press: June 30, 2018
Published online: September 26, 2018
Processing time: 135 Days and 14.7 Hours

Core Tip

Core tip: Current therapeutic interventions in dentistry depend on biomaterials such as metals, polymers, ceramics, and composites. These restorative synthetic dental materials cannot restore the physiological architecture and function of the tissue. Thus, dentistry should move from restorative to regenerative dentistry, with the ability to regrow damaged or missing teeth with their own dental stem cells. Regenerating an entire tooth or individual parts of the tooth require a suitable number of specific stem cell populations for use and implantation. Considering their neural crest origin and ease of availability, gingival-derived mesenchymal stem cells should be considered as an attractive source for stem cells that can be used in regenerative dentistry.