Published online Sep 26, 2015. doi: 10.4252/wjsc.v7.i8.1118
Peer-review started: May 20, 2015
First decision: June 24, 2015
Revised: July 4, 2015
Accepted: July 29, 2015
Article in press: August 3, 2015
Published online: September 26, 2015
Processing time: 129 Days and 22.5 Hours
Stem cells are of global excitement for various diseases including heart diseases. It is worth to understand the mechanism or role of stem cells in the treatment of heart failure. Bone marrow derived stem cells are commonly practiced with an aim to improve the function of the heart. The majority of studies have been conducted with acute myocardial infarction and a few has been investigated with the use of stem cells for treating chronic or dilated cardiomyopathy. Heterogeneity in the treated group using stem cells has greatly emerged. Ever increasing demand for any alternative made is of at most priority for cardiomyopathy. Stem cells are of top priority with the current impact that has generated among physicians. However, meticulous selection of proper source is required since redundancy is clearly evident with the present survey. This review focuses on the methods adopted using stem cells for heart diseases and outcomes that are generated so far with an idea to determine the best therapeutic possibility in order to fulfill the present demand.
Core tip: Heart diseases are most common all over the world and any form of treatment would be well appreciated to enable successful well-being in the patients. Though there are enormous efforts attempted to handle heart diseases, there has been no propounded evidence so far to utilize a particular source of cells globally. In this regard, if the responses all over the world are collectively segregated to a global database, there may be options to identify the best suitable cell source that provides effective cure.