Editorial
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Apr 26, 2015; 7(3): 535-540
Published online Apr 26, 2015. doi: 10.4252/wjsc.v7.i3.535
Origin of cells and network information
Shihori Tanabe
Shihori Tanabe, National Institute of Health Sciences, Tokyo 158-8501, Japan
Author contributions: Tanabe S solely contributed to this paper.
Conflict-of-interest: The author declares that no conflict of interest exists.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Shihori Tanabe, PhD, Senior Researcher, National Institute of Health Sciences, 1-18-1, Kami-yoga, Setagaya-ku, Tokyo 158-8501, Japan. stanabe@nihs.go.jp
Telephone: +81-3-37001141 Fax: +81-3-37076950
Received: December 1, 2014
Peer-review started: December 4, 2014
First decision: January 8, 2015
Revised: January 20, 2015
Accepted: February 9, 2015
Article in press: February 11, 2015
Published online: April 26, 2015
Processing time: 143 Days and 1.4 Hours
Abstract

All cells are derived from one cell, and the origin of different cell types is a subject of curiosity. Cells construct life through appropriately timed networks at each stage of development. Communication among cells and intracellular signaling are essential for cell differentiation and for life processes. Cellular molecular networks establish cell diversity and life. The investigation of the regulation of each gene in the genome within the cellular network is therefore of interest. Stem cells produce various cells that are suitable for specific purposes. The dynamics of the information in the cellular network changes as the status of cells is altered. The components of each cell are subject to investigation.

Keywords: Stem cell; Genome; Network information; Bioinformatics; Gene; Epithelial-mesenchymal transition

Core tip: The cells in the body orchestrate the unique roles of each organ through a cellular network. It is important to investigate alterations in cellular phenotypes and the regulation of genes, the genome and molecules in order to understand the origin of the cells. Insights into the changes in cellular features, including epithelial-mesenchymal transition, and recent database advances are described in this editorial.