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For: Liu XY, Yang LP, Zhao L. Stem cell therapy for Alzheimer's disease. World J Stem Cells 2020; 12(8): 787-802 [PMID: 32952859 DOI: 10.4252/wjsc.v12.i8.787]
URL: https://www.wjgnet.com/1948-0210/full/v12/i8/787.htm
Number Citing Articles
1
Mohammad-Ali Bashirrohelleh, Kowsar Bavarsad, Ali Khodadadi, Mojtaba Shohan, Ali Asadirad. Curcumin-enhanced stem cell exosomes: A novel approach to modulating neuroinflammation and improving cognitive function in a rat model of Alzheimer's disease. European Journal of Pharmacology 2025; 999 doi: 10.1016/j.ejphar.2025.177695
2
Shailendra K. Saxena, Saniya Ansari, Vimal K. Maurya, Swatantra Kumar, Deepak Sharma, Hardeep S. Malhotra, Sneham Tiwari, Chhitij Srivastava, Janusz T. Paweska, Ahmed S. Abdel-Moneim, Soniya Nityanand. Neprilysin-Mediated Amyloid Beta Clearance and Its Therapeutic Implications in Neurodegenerative Disorders. ACS Pharmacology & Translational Science 2024; 7(12) doi: 10.1021/acsptsci.4c00400
3
Fariba Mohebichamkhorami, Zahra Niknam, Mona Khoramjouy, Elmira Heidarli, Rasoul Ghasemi, Simzar Hosseinzadeh, Seyedeh Sarvenaz Mohseni, Arman Hajikarim-Hamedani, Amirhossein Heidari, Yekta Ghane, Matin Mahmoudifard, Hakimeh Zali, Mehrdad Faizi. Brain Homogenate of a Rat Model of Alzheimer's Disease Modifies the Secretome of 3D Cultured Periodontal Ligament Stem Cells: A Potential Neuroregenerative Therapy. Iranian Journal of Pharmaceutical Research 2022; 21(1) doi: 10.5812/ijpr-133668
4
Zhimin Wang, Meiyu Bi, Xiaoshu Zhe, Xiao Wang, Bai Dai, Xiaoyu Han, Bingxu Ren, Hao Liang, Dongjun Liu. Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers. Cell Death Discovery 2024; 10(1) doi: 10.1038/s41420-024-01852-4
5
Heather Wilson, Edoardo Rosario de Natale, Marios Politis. Recent Advances in Neuroimaging Techniques to Assist Clinical Trials on Cell-Based Therapies in Neurodegenerative Diseases. Stem Cells 2022; 40(8) doi: 10.1093/stmcls/sxac039
6
Asmaa Gaber, Osama M. Ahmed, Yasser A. Khadrawy, Khairy M. A. Zoheir, Rasha E. Abo-ELeneen, Mohamed A. Alblihed, Ahlam M. Elbakry. Mesenchymal Stem Cells and Begacestat Mitigate Amyloid-β 25–35-Induced Cognitive Decline in Rat Dams and Hippocampal Deteriorations in Offspring. Biology 2023; 12(7) doi: 10.3390/biology12070905
7
Santa Sarma, Dhruva J. Deka, Prakash Rajak, Damiki Laloo, Trishna Das, Purbajit Chetia, Dipankar Saha, Alakesh Bharali, Bhargab Deka. Potential injectable hydrogels as biomaterials for central nervous system injury: A narrative review. Ibrain 2023; 9(4) doi: 10.1002/ibra.12137
8
Ece Alim, Angelia Greenwell, Ryan Hess, Nicholas Blanco, Jorge H. Torres, Nurettin Sahiner. Stem Cell Therapy: Past, Present, and Future Aspects. Biomedicines 2026; 14(7) doi: 10.3390/biomedicines14071443
9
Fei‐Chien Chang, Matthew Michael James, Yang Zhou, Yoshiki Ando, Hadi M. Zareie, Jihui Yang, Miqin Zhang. Human Neural Stem Cell Expansion in Natural Polymer Scaffolds Under Chemically Defined Condition. Advanced Biology 2024; 8(10) doi: 10.1002/adbi.202400224
10
Jakub Červenka, Jiřina Tylečková, Helena Kupcová Skalníková, Kateřina Vodičková Kepková, Ievgeniia Poliakh, Ivona Valeková, Lucie Pfeiferová, Michal Kolář, Michaela Vaškovičová, Tereza Pánková, Petr Vodička. Proteomic Characterization of Human Neural Stem Cells and Their Secretome During in vitro Differentiation. Frontiers in Cellular Neuroscience 2021; 14 doi: 10.3389/fncel.2020.612560
11
Shaheen Ali, Shouvik Mukherjee, Divya Goel, Anindita Ghosh, Mohammed Faruq. Applications of Stem Cells and derived Exosomes in Neurodegenerative Disorders. 2023;  doi: 10.1007/978-981-99-3848-3_10
12
Yi Wei, Li Li, Yiping Wang, Yan Chen, Zhengyang Li, Chufei Huang, Yangchen Wei, Chiyu Jia, Zuo Wang, Junlin Liao. Stem cell‑mediated modulation of pyroptosis contributes to tissue repair in noninfective inflammatory‑related diseases (Review). International Journal of Molecular Medicine 2024; 53(5) doi: 10.3892/ijmm.2024.5370
13
Mingchao Shi, Fengna Chu, Jie Zhu. Stem cells therapy in neurodegenerative and neuroimmune diseases: Current status of treatments and future prospects. Pharmacological Research 2025; 221 doi: 10.1016/j.phrs.2025.107960
14
Jasvinder Singh Bhatti, Naina Khullar, Jayapriya Mishra, Satinder Kaur, Abhishek Sehrawat, Eva Sharma, Gurjit Kaur Bhatti, Ashley Selman, P. Hemachandra Reddy. Stem cells in the treatment of Alzheimer's disease – Promises and pitfalls. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2023; 1869(6) doi: 10.1016/j.bbadis.2023.166712
15
Cameron Noah Keighron, Sahar Avazzadeh, Katarzyna Goljanek-Whysall, Brian McDonagh, Linda Howard, Thomas Ritter, Leo R. Quinlan. Extracellular Vesicles, Cell-Penetrating Peptides and miRNAs as Future Novel Therapeutic Interventions for Parkinson’s and Alzheimer’s Disease. Biomedicines 2023; 11(3) doi: 10.3390/biomedicines11030728
16
Asaad Abdulrahman Abduljawad, Khadijah B. Alkinani, Aysha Zaakan, Abeer S. AlGhamdi, Alashary Adam Eisa Hamdoon, Batool H. Alshanbari, Ahmed Abdullah Alshehri, Badria Bakheet Alluhaybi, Shahad Othman Ibrahim Alqashi, Ryan Abdulrahman Abduljawad. Targeting Amyloid-β Proteins as Potential Alzheimer’s Disease Therapeutics: Anti-Amyloid Drug Discovery, Emerging Therapeutics, Clinical Trials and Implications for Public Health. Pharmaceuticals 2025; 18(11) doi: 10.3390/ph18111731
17
Azam Karimi, Elham Hoveizi, Lotfollah Khajehpour, Zohreh Ghotbeddin. Behavioral, biochemical, histological, and electrophysiological changes following intracerebral injection of bone marrow stem cell-derived exosomes in male rat models of Alzheimer’s disease. Experimental Brain Research 2027; 245(1) doi: 10.1007/s00221-026-07426-3
18
Swetha Belavadi, Sunil Kumar Kadiri. From pathology to precision therapy: Contemporary and emerging strategies in Alzheimer's disease treatment. European Journal of Pharmacology 2026; 1025 doi: 10.1016/j.ejphar.2026.178913
19
Tong Yin, Yan Liu, Bin He, Baofeng Gong, Jianjian Chu, Chao Gao, Wendanqi Liang, Mengqi Hao, Wenjing Sun, Jianhua Zhuang, Jie Gao, You Yin. Cell primitive-based biomimetic nanomaterials for Alzheimer's disease targeting and therapy. Materials Today Bio 2023; 22 doi: 10.1016/j.mtbio.2023.100789
20
Bhavarth P. Dave, Yesha B. Shah, Kunal G. Maheshwari, Kaif A. Mansuri, Bhadrawati S. Prajapati, Humzah I. Postwala, Mehul R. Chorawala. Pathophysiological Aspects and Therapeutic Armamentarium of Alzheimer’s Disease: Recent Trends and Future Development. Cellular and Molecular Neurobiology 2023; 43(8) doi: 10.1007/s10571-023-01408-7
21
Arianna Minoia, Luca Dalle Carbonare, Jens Christian Schwamborn, Silvia Bolognin, Maria Teresa Valenti. Bone Tissue and the Nervous System: What Do They Have in Common?. Cells 2022; 12(1) doi: 10.3390/cells12010051
22
Charysse Vandendriessche, Dimitrios Kapogiannis, Roosmarijn E. Vandenbroucke. Biomarker and therapeutic potential of peripheral extracellular vesicles in Alzheimer’s disease. Advanced Drug Delivery Reviews 2022; 190 doi: 10.1016/j.addr.2022.114486
23
Faizan Ahmad, Anik Karan, Rashi Sharma, Navatha Shree Sharma, Vaishnavi Sundar, Richard Jayaraj, Sudip Mukherjee, Mark A. DeCoster. Evolving therapeutic interventions for the management and treatment of Alzheimer’s disease. Ageing Research Reviews 2024; 95 doi: 10.1016/j.arr.2024.102229
24
Stephen Z. Fadem, Totini Sagorika Chatterjee. Aging and the Kidney. 2026;  doi: 10.1016/B978-0-443-34069-7.00026-4
25
Ji-Hun Shin, Young Sang Hwang, Bong-Kwang Jung, Seung-Hwan Seo, Do-Won Ham, Eun-Hee Shin. Reduction of Amyloid Burden by Proliferated Homeostatic Microglia in Toxoplasma gondii-Infected Alzheimer’s Disease Model Mice. International Journal of Molecular Sciences 2021; 22(5) doi: 10.3390/ijms22052764
26
Zhao-Xia Song. Advances of induced pluripotent stem cells in Alzheimer’s disease: A bibliometric analysis. New Cell 2024;  doi: 10.61958/NCYV8282
27
Jasleen Kaur, Namisha Kalia, Sunik Malik, Ravish Kumar, Malhar Desai, Anuradha Sharma, Gurpreet Kaur Grewal. Reshaping Healthcare with Cutting-Edge Biomedical Advancements. Advances in Bioinformatics and Biomedical Engineering 2024;  doi: 10.4018/979-8-3693-4439-2.ch009
28
Mohammed Zayed, Sung-Ho Kook, Byung-Hoon Jeong. Potential Therapeutic Use of Stem Cells for Prion Diseases. Cells 2023; 12(19) doi: 10.3390/cells12192413
29
Kayalvizhi Rajendran, Uma Maheswari Krishnan. Mechanistic insights and emerging therapeutic stratagems for Alzheimer’s disease. Ageing Research Reviews 2024; 97 doi: 10.1016/j.arr.2024.102309
30
Jun Chang, Zihang Feng, Yujiao Li, Honglin Lv, Shuzhen Liu, Yongyin Luo, Nan Hao, Lan Zhao, Jianwei Liu. Mesenchymal stem cell-derived extracellular vesicles: A novel promising neuroprotective agent for Alzheimer's disease. Biochemical Pharmacology 2024; 222 doi: 10.1016/j.bcp.2024.116064
31
Fei Xu, Wei Gao, Miao Zhang, Fuyue Zhang, XiaoFei Sun, Bao Wu, Yali Liu, Xue Li, Honglin Li. Diagnostic implications of ubiquitination-related gene signatures in Alzheimer's disease. Scientific Reports 2024; 14(1) doi: 10.1038/s41598-024-61363-1
32
Huan Li, Xinai Shen, Beiyu Zhang, Zheying Zhu. Biologics as Therapeutical Agents Under Perspective Clinical Studies for Alzheimer’s Disease. Molecules 2025; 30(17) doi: 10.3390/molecules30173479
33
Sujatha Krishnamoorthy, Vibhusha Venkatesan, Urbi Roy. A Narrative Review on the Role of Stem Cells in Neurodegenerative Disorders. Journal of Sustainable Chemical Sciences & Technologies 2026; 1 doi: 10.63697/jscst.2026.10135
34
Barbara Miziak, Barbara Błaszczyk, Stanisław J. Czuczwar. Some Candidate Drugs for Pharmacotherapy of Alzheimer’s Disease. Pharmaceuticals 2021; 14(5) doi: 10.3390/ph14050458
35
Faiza Iram, Mohammad Shahid, Jaoud Ansari, Ghulam Md Ashraf, Md. Imtaiyaz Hassan, Asimul Islam. Navigating the Maze of Alzheimer’s disease by exploring BACE1: Discovery, current scenario, and future prospects. Ageing Research Reviews 2024; 98 doi: 10.1016/j.arr.2024.102342
36
Kai Chen, Yanyan Gao, Ninuo Xia, Yusheng Liu, Huiru Wang, Hui Ma, Shengxia Zheng, Fang Fang. Long-term therapeutic effects of allogeneic mesenchymal stem cell transplantation for intrauterine adhesions. Stem Cell Research & Therapy 2024; 15(1) doi: 10.1186/s13287-024-04100-9
37
Rasa Khosrofar, Parmida Nafei, Farshad Zare, Amirhossein Sadrmohammadbagheri, Faranak Zargari, Nassim Rastgar, Sarvin Radvar, Naiyereh Alipour Eskandani, Fateme Hoseinzade, Reza Akhavan Sigari. Translational stem cell therapy for neurodegeneration and CNS trauma: a focused review. Molecular Biology Reports 2026; 53(1) doi: 10.1007/s11033-026-12011-6
38
Therapeutic Potential of Human Stem Cell Implantation in Alzheimer’s Disease. International Journal of Molecular Sciences 2021; 22(18) doi: 10.3390/ijms221810151
39
Miranda Robbins, Venkat Pisupati, Roberta Azzarelli, Samer I. Nehme, Roger A. Barker, Ljiljana Fruk, Gabriele S. Kaminski Schierle. Biofunctionalised bacterial cellulose scaffold supports the patterning and expansion of human embryonic stem cell-derived dopaminergic progenitor cells. Stem Cell Research & Therapy 2021; 12(1) doi: 10.1186/s13287-021-02639-5
40
Yu Zhang, Qi Wu, Yu Ren, Ye Zhang, Linyin Feng. A53T α-synuclein induces neurogenesis impairment and cognitive dysfunction in line M83 transgenic mice and reduces the proliferation of embryonic neural stem cells. Brain Research Bulletin 2022; 182 doi: 10.1016/j.brainresbull.2022.02.010
41
Semira Abdi Beshir, Nadia Hussain, Vineetha Bharathan Menon, Amal H. I. Al Haddad, Rahaf Adnan Kh. Al Zeer, Asim Ahmed Elnour, John Powell. Advancements and Challenges in Antiamyloid Therapy for Alzheimer’s Disease: A Comprehensive Review. International Journal of Alzheimer’s Disease 2024; 2024(1) doi: 10.1155/2024/2052142
42
Prabir Maity, Ayush Spandan Nayak, Gracy Sharma, Suhrit Sinha, Kajal Nishad Nanda, Chinmaya Chandra Das, Soumarshi Das, Rajwinder Kaur, Tanmay Bagade. Stem Cell Therapy in Alzheimer’s Disease: a Scoping Review of Safety, Efficacy and Clinical Insights. Current Stem Cell Reports 2026; 12(1) doi: 10.1007/s40778-026-00263-8
43
Yujie Zhang, Jie Chen, Yanru Li, Bin Jiao, Shilin Luo. Disease-modifying therapies for Alzheimer’s disease: Clinical trial progress and opportunity. Ageing Research Reviews 2025; 103 doi: 10.1016/j.arr.2024.102595
44
Konstantin B. Yenkoyan, Maria M. Kotova, Kirill V. Apukhtin, David S. Galstyan, Tamara G. Amstislavskaya, Tatyana Strekalova, Murilo S. de Abreu, Vergine A. Chavushyan, Lee Wei Lim, Longen Yang, Denis B. Rosemberg, Allan V. Kalueff. Experimental modeling of Alzheimer's disease: Translational lessons from cross‐taxon analyses. Alzheimer's & Dementia 2025; 21(5) doi: 10.1002/alz.70273
45
Yuxin Jing, Wei Zheng, Zhou Zhou, Haiyang Yao, Wenchuan Zhang, Yilun Wu, Zimo Guo, Chenxuan Huang, Xianli Wang. Recent research advances of c-fos in regulating cell senescence. Archives of Biochemistry and Biophysics 2025; 769 doi: 10.1016/j.abb.2025.110423
46
Wenwen Li, Huihui Zhang, Lianglong Chen, Chaoyang Huang, Ziwei Jiang, Hai Zhou, Xinxi Zhu, Xiaoyang Liu, Zesen Zheng, Qiuyi Yu, Yufang He, Yanbin Gao, Jun Ma, Lei Yang. Cell membrane-derived nanovesicles as extracellular vesicle-mimetics in wound healing. Materials Today Bio 2025; 31 doi: 10.1016/j.mtbio.2025.101595
47
Stephen Adeniyi Adefegha. Handbook of Animal Models and its Uses in Cancer Research. 2022;  doi: 10.1007/978-981-19-1282-5_40-1
48
Mohammad Amine Reslan, Hawraa Issa, Nadine Al-Haj, Stanley Ibeh, Yara Yehya, Houssein Hajj Hassan, Firas Kobeissy, Ali H. Eid, Kazem Zibara, Abdullah Shaito. Role of Micronutrients in Brain Health. Nutritional Neurosciences 2022;  doi: 10.1007/978-981-16-6467-0_15
49
Shuran Li, Yongbiao Li, Wenjing Sun, Zhiping Qin, Yangyang Lu, Yujia Song, Man Ga, Farong Yuan, Qingshan Liu. Sanwei DouKou Decoction ameliorate Alzheimer disease by increasing endogenous neural stem cells proliferation through the Wnt/β-catenin signalling pathway. Journal of Ethnopharmacology 2023; 309 doi: 10.1016/j.jep.2023.116364
50
Daria Y. Zhdanova, Natalia V. Bobkova, Alina V. Chaplygina, Elena V. Svirshchevskaya, Rimma A. Poltavtseva, Anastasia A. Vodennikova, Vasiliy S. Chernyshev, Gennadiy T. Sukhikh. Effect of Small Extracellular Vesicles Produced by Mesenchymal Stem Cells on 5xFAD Mice Hippocampal Cultures. International Journal of Molecular Sciences 2025; 26(9) doi: 10.3390/ijms26094026
51
Shivam Rajput, Rishabha Malviya, Shiv Bahadur, Dinesh Puri. Recent Updates on the Development of Therapeutics for the Targeted Treatment of Alzheimer’s Disease. Current Pharmaceutical Design 2023; 29(35) doi: 10.2174/0113816128274618231105173031
52
Kratika Pandey, Priyanka Srivastava, Swaroop Kumar Pandey, Surabhi Johari, Priyanka Bhatnagar, Madhavi Sonane, Anuja Mishra. Stem Cells as a Novel Source for Regenerative Medicinal Applications in Alzheimer's Disease: An Update. Current Molecular Medicine 2025; 25(2) doi: 10.2174/0115665240334785240913071442
53
Marva Lachish, Nina Fainstein, Tal Ganz, Lihi Sofer, Tamir Ben-Hur. Failure of Alzheimer’s Mice Brain Resident Neural Precursor Cells in Supporting Microglia-Mediated Amyloid β Clearance. Cells 2022; 11(5) doi: 10.3390/cells11050876
54
Nima Ghasemi, Hossein Azizi, Ali Qorbanee, Thomas Skutella. From unipotency to pluripotency: deciphering protein networks and signaling pathways in the generation of embryonic stem-like cells from murine spermatogonial stem cells. BMC Genomics 2025; 26(1) doi: 10.1186/s12864-025-11612-y
55
Ali Mirzaei, Pouria Rezaei, Reza Golchin Vafa, Saleheh Jahani, Reza Arefnezhad, Hossein Fatemian, Mohammad Hossein Nikoo, Amirhossein Sahebkar, Fatemeh Rezaei‐Tazangi. The Therapeutic Potential of Stem Cell Therapy for Doxorubicin‐Induced Cardiotoxicity: A Narrative Review. Health Science Reports 2026; 9(8) doi: 10.1002/hsr2.72924
56
Shrishti Madhan, Anisha Mehta, Anushka Santoshkumar, Srisri Satishkarthik, K.N. Aruljothi. Stem Cell Interventions in the Treatment of Alzheimer's Disease. Current Stem Cell Research & Therapy 2025; 20(4) doi: 10.2174/011574888X308941240507050855
57
Tyasno Koeshermanto, Muhammad Aditya Ferdiansyah, Raden Andi Ario Tedjo, An’nurihza Zidhan Azhara, Stefanus Erdana Putra. Bridging the translational gap in Alzheimer’s disease: A bibliometric and evidence-based assessment of secretome and stem cell therapeutics. Archives of Gerontology and Geriatrics Plus 2026; 3(3) doi: 10.1016/j.aggp.2026.100295
58
Xiaokun Chen, Shenzhong Jiang, Renzhi Wang, Xinjie Bao, Yongning Li. Neural Stem Cells in the Treatment of Alzheimer’s Disease: Current Status, Challenges, and Future Prospects. Journal of Alzheimer’s Disease 2023; 94(s1) doi: 10.3233/JAD-220721
59
Wenjing Lu, Junqiang Yan, Hongfang Feng. Stem Cell and EV/sEV Strategies for Neuroimmune Niche Reprogramming in Selected CNS Disorders: Mechanisms, Engineered Delivery, and Translational Readiness. CNS Neuroscience & Therapeutics 2026; 32(10) doi: 10.1002/cns.71211
60
Roman Sattarov, Håkan Toresson, Camilla Orbjörn, Niklas Mattsson-Carlgren. Direct Conversion of Fibroblast into Neurons for Alzheimer’s Disease Research: A Systematic Review. Journal of Alzheimer’s Disease 2023; 95(3) doi: 10.3233/JAD-230119
61
Osama Hamadelseed, Thomas Skutella. Stem cell-based therapeutic strategies for down syndrome and Alzheimer’s disease. Stem Cell Research & Therapy 2025; 16(1) doi: 10.1186/s13287-025-04556-3
62
Chidiebere Emmanuel Okechukwu. Deciphering and manipulating the epigenome for the treatment of Parkinson’s and Alzheimer’s disease. MGM Journal of Medical Sciences 2021; 8(2) doi: 10.4103/mgmj.mgmj_90_20
63
Masanori A. Murayama. The past and present of therapeutic strategy for Alzheimer’s diseases: potential for stem cell therapy. Experimental Animals 2023; 72(3) doi: 10.1538/expanim.22-0164
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Mohamed A. Zayed, Samar Sultan, Hashem O. Alsaab, Shimaa Mohammad Yousof, Ghadeer I. Alrefaei, Nouf H. Alsubhi, Saleh Alkarim, Kholoud S. Al Ghamdi, Sali Abubaker Bagabir, Ankit Jana, Badrah S. Alghamdi, Hazem M. Atta, Ghulam Md Ashraf. Stem-Cell-Based Therapy: The Celestial Weapon against Neurological Disorders. Cells 2022; 11(21) doi: 10.3390/cells11213476
65
Md. Zamshed Alam Begh, Mehrukh Zehravi, Md. Abdul Kuddus Bhuiyan, M. Raju Molla, Kannan Raman, Talha Bin Emran, Md. Habib Ullah, Irfan Ahmad, Hamid Osman, Mayeen Uddin Khandaker. Recent advances in stem cell approaches to neurodegeneration: A comprehensive review with mechanistic insight. Pathology - Research and Practice 2025; 271 doi: 10.1016/j.prp.2025.156013
66
Dheeraj Sharma, Shriyansh Srivastava. Stem Cell Therapeutics. 2025;  doi: 10.1002/9781394313785.ch7
67
Leila Alidoust, Mohammad Akhoondian, Amir homayoun Atefi, Mohammad-Hossein Keivanlou, Mojtaba Hedayati Ch, Adele Jafari. Stem cell-conditioned medium is a promising treatment for Alzheimer's disease. Behavioural Brain Research 2023; 452 doi: 10.1016/j.bbr.2023.114543
68
Gino A. Kurian. Phospholipases in Physiology and Pathology. 2023;  doi: 10.1016/B978-0-443-15177-4.00003-0
69
Julianna Lilienberg, Zoltán Hegyi, Eszter Szabó, Edit Hathy, András Málnási-Csizmadia, János M. Réthelyi, Ágota Apáti, László Homolya. Pharmacological Modulation of Neurite Outgrowth in Human Neural Progenitor Cells by Inhibiting Non-muscle Myosin II. Frontiers in Cell and Developmental Biology 2021; 9 doi: 10.3389/fcell.2021.719636
70
Sowmiya S, Dhivya L.S., Praveen Rajendran, Harikrishnan N, Ankul Singh S. Exploring the potential of probiotics in Alzheimer's disease and gut dysbiosis. IBRO Neuroscience Reports 2024; 17 doi: 10.1016/j.ibneur.2024.11.004
71
Bridget Martinez, Philip V. Peplow. Biomaterial and tissue-engineering strategies for the treatment of brain neurodegeneration. Neural Regeneration Research 2022; 17(10) doi: 10.4103/1673-5374.336132
72
Il-Kwon Kim, Jun-Hee Park, Bomi Kim, Ki-Chul Hwang, Byeong-Wook Song. Recent advances in stem cell therapy for neurodegenerative disease: Three dimensional tracing and its emerging use. World Journal of Stem Cells 2021; 13(9): 1215-1230 doi: 10.4252/wjsc.v13.i9.1215
73
Bahar Ataei, Mahsa Hokmabadi, Sahar Asadi, Elnaz Asadifard, Seyed Mohsen Aghaei Zarch, Sajad Najafi, Saeid Bagheri-Mohammadi. A review of the advances, insights, and prospects of gene therapy for Alzheimer’s disease: A novel target for therapeutic medicine. Gene 2024; 912 doi: 10.1016/j.gene.2024.148368
74
Jing Zhang, Tianze Sun, Wentao Zhang, Ming Yang, Zhonghai Li. Autologous cultured adipose derived mesenchymal stem cells combined with hyaluronic acid hydrogel in the treatment of discogenic low back pain: a study protocol for a phase II randomised controlled trial. BMJ Open 2022; 12(10) doi: 10.1136/bmjopen-2022-063925
75
Fengqin Sun, Yulin Zhang, Xinran Wu, Xu Xu, Chaodie Zhu, Wei Huang. Breviscapine Combined with BMSCs Reduces Aβ Deposition in Rat with Alzheimer's Disease by Regulating Circular RNA ciRS-7. Current Molecular Medicine 2023; 23(1) doi: 10.2174/1566524022666220113151044
76
Rahul Kumar, Srushti Mahajan, Ujala Gupta, Jitendra Madan, Chandraiah Godugu, Santosh Kumar Guru, Pankaj Kumar Singh, Prachi Parvatikar, Indrani Maji. Targeted Therapy for the Central Nervous System. 2025;  doi: 10.1016/B978-0-443-23841-3.00009-1
77
A. D. Voronova, E. K. Karsuntseva, V. S. Shishkina, A. V. Chadin, G. A. Fursa, P. I. Gurin, T. V. Kuznetsova, I. V. Reshetov, S. V. Shport, O. V. Stepanova, V. P. Chekhonin. Clinical Trials of Cell Products for the Treatment of Alzheimer’s Disease (Review). Bulletin of Experimental Biology and Medicine 2025; 180(1) doi: 10.1007/s10517-026-06590-4
78
Deepak Kumar, Piyush Anand, Shashi Kant Singh. Proposed Therapeutic Strategy to Combat Alzheimer’s Disease by Targeting Beta and Gamma Secretases. Current Alzheimer Research 2025; 22(5) doi: 10.2174/0115672050380899250602042028
79
A. E. Hernández, E. García, Huseyin Sumer. Mesenchymal Stem Cell Therapy for Alzheimer’s Disease. Stem Cells International 2021; 2021 doi: 10.1155/2021/7834421
80
Yang-Yang Zhao. Trends and hotspots in bone marrow mesenchymal stem cell research for Alzheimer’s disease: a bibliometric study. Integrate Medicine 2025;  doi: 10.61958/IMZR5742
81
Federica Cavion, Michele Cacioppo, Susanna Bosi, Michela Carlin, Silvio Sosa, Maurizio Prato, Marco Pelin. Differentiation properties of 3D scaffolds nanostructured with multi-walled carbon nanotubes on human induced pluripotent stem cells. RSC Advances 2025; 15(53) doi: 10.1039/D5RA06688C
82
Moawiah M Naffaa. The Fate and Dynamics of Neural Stem Cells (NSCs) and Their Neurogenic Decline in Alzheimer’s Disease. Lifespan Development and Mental Health 2025; 1(2) doi: 10.70322/ldmh.2025.10005
83
Arun Soni, Mahima Sukhadia, Pratham Shah, Nilay Solanki. Nanotherapeutics for Treating Neurodegenerative Disorders. 2026;  doi: 10.1016/B978-0-443-33623-2.00005-2
84
Shadaan Ahmad, Ritu Sharma, Neha parveen, Rabiya Basri, Lubna Ahmad, Mohd. Aqil, Nazeer Hasan, Farhan Jalees Ahmad. Nano-decoys- future of drug delivery for the treatment of arthritis- a review. Biomaterials Advances 2026; 180 doi: 10.1016/j.bioadv.2025.214598
85
Can Mei, Jianbo Zhan, Shuzhen Zhu, Yutong Zhang, Chang‐e Xiong, Jia Wang, Yu Jia Xu, Hua Zhong, Jing Cheng. Advances of therapy for Alzheimer's disease: An updated review. Brain‐X 2024; 2(3) doi: 10.1002/brx2.68
86
Aditya Bhatt, Harshita Bhardwaj, Priyanka Srivastava. Mesenchymal stem cell therapy for Alzheimer’s disease: A novel therapeutic approach for neurodegenerative diseases. Neuroscience 2024; 555 doi: 10.1016/j.neuroscience.2024.07.019
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Xue Li, Zhenhuan Wu, Chao Yao, Pengye Zhang, Qingyu Zhu, Shunxue Nan, Lei Xiao, Shengcai Qi. Porphyromonas gingivalis Promotes Neuroinflammation by Microglial Ferroptosis via NOX4/PPAR-α/PGC-1α Pathway . Research 2026; 9 doi: 10.34133/research.1163
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Miriana Caporlingua, Jole Castellano, Angelo Quartarone, Rosella Ciurleo. Research on Alzheimer Disease in Italy: A Narrative Review of Pharmacological and Non-Pharmacological Interventions. Neurology International 2025; 17(12) doi: 10.3390/neurolint17120196
89
Veerta Sharma, Thakur Gurjeet Singh, Amarjot Kaur, Ashi Mannan, Sonia Dhiman. Brain-Derived Neurotrophic Factor: A Novel Dynamically Regulated Therapeutic Modulator in Neurological Disorders. Neurochemical Research 2023; 48(2) doi: 10.1007/s11064-022-03755-1
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Stephan En Jie Chee, Egle Solito. The Impact of Ageing on the CNS Immune Response in Alzheimer’s Disease. Frontiers in Immunology 2021; 12 doi: 10.3389/fimmu.2021.738511
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Rui Wang, Yi Zhu, Lan-Fang Qin, Zhi-Guo Xu, Xi-Ren Gao, Chong-Bin Liu, Guo-Tong Xu, Yi-Zhu Chen. Comprehensive Bibliometric Analysis of Stem Cell Research in Alzheimer’s Disease from 2004 to 2022. Dementia and Geriatric Cognitive Disorders 2023; 52(2) doi: 10.1159/000528886
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Abdul Haseeb, Muhammad Ashir Shafique, Abdullah Mussarat, Mohammad Arham Siddiq, Muhammad Saqlain Mustafa. Stem cell therapy, a novel treatment option for Alzheimer’s disease and multiple sclerosis?. International Journal of Surgery: Global Health 2023; 6(4) doi: 10.1097/GH9.0000000000000193
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Efficacy and Safety of Stem Cell Therapy in Alzheimer's Disease: A Review. Current Stem Cell Research & Therapy 2025; 20(2) doi: 10.2174/011574888X267673231120061600
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Siddharth Shah, Hadeel M. Mansour, Brandon Lucke-Wold. Advances in Stem Cell Therapy for Huntington’s Disease: A Comprehensive Literature Review. Cells 2025; 14(1) doi: 10.3390/cells14010042
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Allison B. Reiss, Dalia Muhieddine, Berlin Jacob, Michael Mesbah, Aaron Pinkhasov, Irving H. Gomolin, Mark M. Stecker, Thomas Wisniewski, Joshua De Leon. Alzheimer’s Disease Treatment: The Search for a Breakthrough. Medicina 2023; 59(6) doi: 10.3390/medicina59061084
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Akash Chaurasiya, Sumeet Katke, Kanan Panchal, Jayabalan Nirmal. Nanomedicine-Based Approaches for the Treatment of Dementia. 2023;  doi: 10.1016/B978-0-12-824331-2.00001-7
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Davin Devara, Bhupender Sharma, Gunjan Goyal, Daniela Rodarte, Aditi Kulkarni, Nathan Tinu, Ayana Pai, Subodh Kumar. MiRNA‐501‐3p and MiRNA‐502‐3p: A promising biomarker panel for Alzheimer's disease. Clinical and Translational Medicine 2025; 15(7) doi: 10.1002/ctm2.70389
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Mengyu Liang, Zhichao Liu, Zhonghui Zhang, Yuxiao Mei, Yang Tian. A two-photon ratiometric fluorescent probe for real-time imaging and quantification of NO in neural stem cells during activation regulation. Chemical Science 2022; 13(15) doi: 10.1039/D2SC00326K
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Xiangyu Ma, Ho Jin Lee, Dong Oh. Kim, Young Do Kwon, Geun-Hyoung Ha, Chung Kwon Kim, Hyun Nam, Je Young Yeon, Kyunghoon Lee, Sun-Ho Lee, Kyeung Min Joo. Identification of allogeneic and xenogeneic neural stem cells' immunogenicity in the brain and strategies to alleviate transplantation rejection. Transplant Immunology 2025; 92 doi: 10.1016/j.trim.2025.102247
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Jun Chang, Yujiao Li, Xiaoqian Shan, Xi Chen, Xuhe Yan, Jianwei Liu, Lan Zhao. Neural stem cells promote neuroplasticity: a promising therapeutic strategy for the treatment of Alzheimer’s disease. Neural Regeneration Research 2024; 19(3) doi: 10.4103/1673-5374.380874
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Ran Wang, Yilin Qi, Jinjin Liu, Yang Li, Hongde An, Heping Wang, Jie Song, Wenzhuo Hu, Shaochun Wu, Leqian Yu, Yao Chen, Xue Xue. Metal-organic polyhedra maintain the self-renewal of embryonic stem cells. Nature Communications 2025; 16(1) doi: 10.1038/s41467-025-63811-6
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Qiang Fu, Rui Qiu, Shang Li, Yuxiang Qin, Ziyi Lu, Shanxin Liyao, Zimo Yang, Xiang Cheng, Yuewen Chen, Huan Xu, Yong Cheng. ECHS1: pathogenic mechanisms, experimental models, and emerging therapeutic strategies. Orphanet Journal of Rare Diseases 2025; 20(1) doi: 10.1186/s13023-025-03959-y
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Yoganchal Mishra, Sarika Singh, Neelam Yadav. Neurodegenerative Diseases: Multifactorial Degenerative Processes, Biomarkers and Therapeutic Approaches (First Edition). 2022;  doi: 10.2174/9789815040913122010008
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Caidi Ying, Jiahao Zhang, Haocheng Zhang, Shiqi Gao, Xiaoming Guo, Jun Lin, Haijian Wu, Yuan Hong. Stem cells in central nervous system diseases: Promising therapeutic strategies. Experimental Neurology 2023; 369 doi: 10.1016/j.expneurol.2023.114543
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Ramyar Rahimi Darehbagh, Seyedeh Asrin Seyedoshohadaei, Rojin Ramezani, Nima Rezaei. Stem cell therapies for neurological disorders: current progress, challenges, and future perspectives. European Journal of Medical Research 2024; 29(1) doi: 10.1186/s40001-024-01987-1
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A. D. Voronova, E. K. Karsuntseva, O. V. Stepanova, A. V. Chadin, V. V. Shishkina, S. S. Andretsova, G. A. Fursa, S. V. Shport, I. V. Reshetov, V. P. Chekhonin. Modeling of Alzheimer’s Disease to Study the Efficacy of Cell Therapy (Review). Bulletin of Experimental Biology and Medicine 2023; 175(4) doi: 10.1007/s10517-023-05899-8
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Dhrupad Banerjee, Arghya Bhattacharya, Abhijeet Puri, Shubham Munde, Nobendu Mukerjee, Popat Mohite, Syeda W. Kazmi, Abhishek Sharma, Taha Alqahtani, Humood Al Shmrany. Innovative approaches in stem cell therapy: revolutionizing cancer treatment and advancing neurobiology – a comprehensive review. International Journal of Surgery 2024; 110(12) doi: 10.1097/JS9.0000000000002111
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Huiyue Li, Hongliang Liu, Michael W. Lutz, Sheng Luo. Novel Genetic Variants in TP37, PIK3R1, CALM1, and PLCG2 of the Neurotrophin Signaling Pathway Are Associated with the Progression from Mild Cognitive Impairment to Alzheimer’s Disease. Journal of Alzheimer's Disease 2023; 91(3) doi: 10.3233/JAD-220680
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Xiao-xia Ban, Hao Wan, Xin-xing Wan, Ya-ting Tan, Xi-min Hu, Hong-xia Ban, Xin-yu Chen, Kun Huang, Qi Zhang, Kun Xiong. Copper Metabolism and Cuproptosis: Molecular Mechanisms and Therapeutic Perspectives in Neurodegenerative Diseases. Current Medical Science 2024; 44(1) doi: 10.1007/s11596-024-2832-z
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Mahmoud Tarek Hefnawy, Nour Shaheen, Kholoud Elsamman, Muhammad Ashraf Husain, Naydeen Mostafa, Mohamed Hazem Khalil, Yara Amro, Mostafa Meshref. Essential Guide to Neurodegenerative Disorders. 2025;  doi: 10.1016/B978-0-443-15702-8.00032-4
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Ramón Cacabelos, Iván Carrera, Olaia Martínez-Iglesias, Natalia Cacabelos, Vinogran Naidoo. What is the gold standard model for Alzheimer’s disease drug discovery and development?. Expert Opinion on Drug Discovery 2021; 16(12) doi: 10.1080/17460441.2021.1960502
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Ying Liu, Leilei Jiang, Wenbo Song, Chenxi Wang, Shiting Yu, Juhui Qiao, Xinran Wang, Chenrong Jin, Daqing Zhao, Xueyuan Bai, Peiguang Zhang, Siming Wang, Meichen Liu. Ginsenosides on stem cells fate specification—a novel perspective. Frontiers in Cell and Developmental Biology 2023; 11 doi: 10.3389/fcell.2023.1190266
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Navatha Shree Sharma, Anik Karan, Donghee Lee, Zheng Yan, Jingwei Xie. Advances in Modeling Alzheimer's Disease In Vitro. Advanced NanoBiomed Research 2021; 1(12) doi: 10.1002/anbr.202100097
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Engrafted stem cell therapy for Alzheimer's disease: A promising treatment strategy with clinical outcome. Journal of Controlled Release 2021; 338 doi: 10.1016/j.jconrel.2021.09.007
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Da Yeon Lee, Sung Eun Lee, Do Hyeon Kwon, Saraswathy Nithiyanandam, Mi Ha Lee, Ji Su Hwang, Shaherin Basith, Jung Hwan Ahn, Tae Hwan Shin, Gwang Lee, Jane Ru Choi. Strategies to Improve the Quality and Freshness of Human Bone Marrow-Derived Mesenchymal Stem Cells for Neurological Diseases. Stem Cells International 2021; 2021 doi: 10.1155/2021/8444599
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Rishika Dhapola, Sneha Kumari, Prajjwal Sharma, Mohit Paidlewar, Balachandar Vellingiri, Ssang-Goo Cho, Ahmed Abdal Dayem, Bikash Medhi, Dibbanti HariKrishnaReddy. Stem cells and derived growth factors in Alzheimer’s disease: mechanistic insights and translational perspectives. Inflammopharmacology 2026;  doi: 10.1007/s10787-026-02418-9
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Emad M. Elzayat, Sherif A. Shahien, Ahmed A. El-Sherif, Mohamed Hosney. miRNAs and Stem Cells as Promising Diagnostic and Therapeutic Targets for Alzheimer’s Disease. Journal of Alzheimer’s Disease 2023; 94(s1) doi: 10.3233/JAD-221298
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Jihyun Lee, In Gyoung Ju, Yeon-Jin Lim, Jin Hee Kim, Seungmin Lee, Yujin Choi, Myung Sook Oh, Jaehoon Kim, Dokyoung Kim. Dimethysiloxane polymer for the effective transdermal delivery of donepezil in Alzheimer's disease treatment. Biomaterials Science 2025; 13(5) doi: 10.1039/D4BM01368A
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Rashi Srivastava, Aidong Li, Tirtharaj Datta, Niraj Kumar Jha, Salehikram Talukder, Saurabh Kumar Jha, Zhe-Sheng Chen. Advances in stromal cell therapy for management of Alzheimer’s disease. Frontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.955401
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Teeba Athar, K. Al Balushi, Shah Alam Khan. Recent advances on drug development and emerging therapeutic agents for Alzheimer’s disease. Molecular Biology Reports 2021; 48(7) doi: 10.1007/s11033-021-06512-9
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Pritama Paul, Abhishek Bhattacharjee, Susanta Kumar Bordoloi, Uttam Kumar Paul. The evolution of Alzheimer’s disease therapies: A comprehensive review. Annals of Medical Science & Research 2024; 3(1) doi: 10.4103/amsr.amsr_37_23
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Madhan Jeyaraman, Ramya Lakshmi Rajendran, Sathish Muthu, Naveen Jeyaraman, Shilpa Sharma, Saurabh Kumar Jha, Purushothaman Muthukanagaraj, Chae Moon Hong, Lucas Furtado da Fonseca, José Fábio Santos Duarte Lana, Byeong-Cheol Ahn, Prakash Gangadaran. An update on stem cell and stem cell-derived extracellular vesicle-based therapy in the management of Alzheimer’s disease. Heliyon 2023; 9(7) doi: 10.1016/j.heliyon.2023.e17808
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César Cáceres, Bernardita Heusser, Alexandra Garnham, Ewa Moczko. The Major Hypotheses of Alzheimer’s Disease: Related Nanotechnology-Based Approaches for Its Diagnosis and Treatment. Cells 2023; 12(23) doi: 10.3390/cells12232669
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Negin Biglari, Amir Mehdizadeh, Mahsa Vafaei Mastanabad, Mohammad Hesam Gharaeikhezri, Ladan Gol Mohammad Pour Afrakoti, Hooman Pourbala, Mehdi Yousefi, Mohammad Sadegh Soltani-Zangbar. Application of mesenchymal stem cells (MSCs) in neurodegenerative disorders: History, findings, and prospective challenges. Pathology - Research and Practice 2023; 247 doi: 10.1016/j.prp.2023.154541
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Mehul R. Chorawala, Aayushi C. Shah, Aanshi J. Pandya, Nirjari R. Kothari, Bhupendra Gopalbhai Prajapati. Alzheimer's Disease and Advanced Drug Delivery Strategies. 2024;  doi: 10.1016/B978-0-443-13205-6.00009-1
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Yung-Chih Kuo, Sourav De. RETRACTED: Development of carbon dots to manage Alzheimer's disease and Parkinson's disease. Journal of the Taiwan Institute of Chemical Engineers 2023; 146 doi: 10.1016/j.jtice.2023.104799
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Ekaterina Belousova, Diana Salikhova, Yaroslav Maksimov, Vladimir Nebogatikov, Anastasiya Sudina, Dmitry Goldshtein, Aleksey Ustyugov. Proposed Mechanisms of Cell Therapy for Alzheimer’s Disease. International Journal of Molecular Sciences 2024; 25(22) doi: 10.3390/ijms252212378
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Abhinav Gupta, Arya Ghosh, Neelima Sharma, Bapi Gorain. Advancements in Stem Cell Research for Effective Therapies Against Alzheimer’s Disease: Current Investigation and Future Insight. Molecular Neurobiology 2025; 62(11) doi: 10.1007/s12035-025-05003-3
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Kun Jiang, Yongqi Zhu, Lei Zhang. Hippocampus - Cytoarchitecture and Diseases. 2022;  doi: 10.5772/intechopen.100334
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Fangyi Zhao, Bingjin Li, Wei Yang, Tongtong Ge, Ranji Cui. Brain–immune interaction mechanisms: Implications for cognitive dysfunction in psychiatric disorders. Cell Proliferation 2022; 55(10) doi: 10.1111/cpr.13295
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Stephen Adeniyi Adefegha. Handbook of Animal Models and its Uses in Cancer Research. 2023;  doi: 10.1007/978-981-19-3824-5_40
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Elham Hoveizi, Golamreza Bijavi, Hoda Parsa. Advancing Cell Therapy to Enhance Passive Avoidance Memory: Integrative Approaches Combining Neural-Like Cells and Rosmarinic Acid Through Behavioral, Molecular, and Histological Analyses. Neurochemical Research 2025; 50(6) doi: 10.1007/s11064-025-04581-x
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Ana R. Monteiro, Daniel J. Barbosa, Fernando Remião, Renata Silva. Alzheimer’s disease: Insights and new prospects in disease pathophysiology, biomarkers and disease-modifying drugs. Biochemical Pharmacology 2023; 211 doi: 10.1016/j.bcp.2023.115522
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Akram Tayanloo-Beik, Amirabbas Nikkhah, Peyvand Parhizkar Roudsari, Hamidreza Aghayan, Mostafa Rezaei-Tavirani, Ensieh Nasli-Esfahani, Ahmad Rezazadeh Mafi, Mohsen Nikandish, Fatemeh Fazeli Shouroki, Babak Arjmand, Bagher Larijani. Cell Biology and Translational Medicine, Volume 18. Advances in Experimental Medicine and Biology 2022; 1409 doi: 10.1007/5584_2022_734
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Mar Pacheco-Herrero, Luis O. Soto-Rojas, Heidy Reyes-Sabater, Linda Garcés-Ramirez, Fidel de la Cruz López, Ignacio Villanueva-Fierro, José Luna-Muñoz. Current Status and Challenges of Stem Cell Treatment for Alzheimer’s Disease. Journal of Alzheimer's Disease 2021; 84(3) doi: 10.3233/JAD-200863
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Faizan Ahmad, Punya Sachdeva. A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease. AGING MEDICINE 2022; 5(3) doi: 10.1002/agm2.12216
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Jing Zhang, Wentao Zhang, Tianze Sun, Jinzuo Wang, Ying Li, Jing Liu, Zhonghai Li, Gianpaolo Papaccio. The Influence of Intervertebral Disc Microenvironment on the Biological Behavior of Engrafted Mesenchymal Stem Cells. Stem Cells International 2022; 2022 doi: 10.1155/2022/8671482
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Yang Yang, Qi Ji, Jiu-jian Cao, Ying-jie Zhang, Qiao-Qiao Li, Shi-hong Liu, Ming-Hui Kong, Yu Xiong, Mei-ming Xie, Zhi-ru zhu. Overactivation of the inward rectifier K+ channel 2.1 modulates intrinsic excitability of adult-born granule cells in the male Alzheimer’s APP/PS1 mouse model. Neuroscience 2025; 584 doi: 10.1016/j.neuroscience.2025.08.011
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Boyu Zhang, Yajun Bi, Kang Wang, Xingjun Guo, Zeming Liu, Jia Li, Min Wu. Stem Cell-Derived Extracellular Vesicles: Promising Therapeutic Opportunities for Diabetic Wound Healing. International Journal of Nanomedicine 2024;  doi: 10.2147/IJN.S461342
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Sayali Mukherjee, Garima Yadav, Rajnish Kumar. Recent trends in stem cell-based therapies and applications of artificial intelligence in regenerative medicine. World Journal of Stem Cells 2021; 13(6): 521-541 doi: 10.4252/wjsc.v13.i6.521
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Shima Mehrabadi. Uncovering the Healing Power of Stem Cells: Harnessing Regenerative Therapies for Alzheimer's Disease. Current Aging Science 2025; 18(3) doi: 10.2174/0118746098334856250106055739
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Mitali Maji, Subhas Khajanchi. Mathematical models on Alzheimer's disease and its treatment: A review. Physics of Life Reviews 2025; 52 doi: 10.1016/j.plrev.2025.01.004