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Observational Study
Copyright ©The Author(s) 2025.
World J Gastroenterol. Oct 21, 2025; 31(39): 110288
Published online Oct 21, 2025. doi: 10.3748/wjg.v31.i39.110288
Table 1 Baseline demographic and clinical characteristics of two groups, mean ± SD
Variables
TILL group
MMH group
Z/χ2
P value
Gender, male39420.2020.653
Female5148
Age (years)41.71 ± 9.2640.53 ± 9.00-0.8990.369
Disease duration (years)4.67 ± 2.494.86 ± 2.38-0.6850.494
Table 2 Comparison of primary outcome between two groups, n (%)
Grade
TILL group
MMH group
χ2
P value
Ineffective0 (0.00)2 (2.22)9.5970.022
Effective 1 (1.11)9 (10.00)
Markedly effective7 (7.78)9 (10.00)
Cured82 (91.1)70 (77.80)
Total90 (100.00)90 (100.00)
Table 3 Comparison of secondary outcomes between two groups
Variables
TILL group
MMH group
Z/χ2
P value
Rate of recurrence, n (%)02 (2.22)2.0220.155
Healing time (days), mean ± SD33.24 ± 4.0635.94 ± 5.38-3.2160.001
Table 4 Comparison of anal pain scores between two groups, mean ± SD
Group
n
Anal pain (day 1)
Anal pain (day 3)
Anal pain (day 7)
TILL group901.01 ± 0.952.60 ± 1.154.01 ± 1.12
MMH group901.23 ± 0.842.98 ± 0.794.47 ± 1.19
Z-2.119-2.667-2.249
P value0.0340.0080.025
Table 5 Comparison of safety measurements between two groups, mean ± SD
Group
Cases
Anal edema
Anal tenesmus
Anal stenosis
Anal incontinence
TILL group901.02 ± 0.690.91 ± 0.650.14 ± 0.380.20 ± 0.43
MMH group901.39 ± 0.680.96 ± 0.630.39 ± 0.560.18 ± 0.41
Z-3.488-0.474-3.455-0.384
P value0.0000.6360.0010.701