Prevalence of metabolic dysfunction-associated fatty liver disease among health check-up attendees: A retrospective study conducted in Vietnam

Table 1 General characteristics of the study population and according to the presence of metabolic dysfunction-associated fatty liver disease, n (%)/median (interquartile range)

Variable	Total (n = 331)	MAFLD (n = 97)	Non-MAFLD (n = 234)	P value
Age (years) (mean ± SD)	44.99 ± 10.69	48.02 ± 10.22	43.73 ± 10.64	< 0.001
Age				< 0.001
Male	164 (49.55)	73 (75.26)	91 (38.89)
Female	167 (50.45)	24 (24.74)	143 (61.11)
BMI (kg/m2)	23.1 (21.3-25.3)	25.4 (23.7-26.8)	22.4 (20.7-23.8)	< 0.001
Underweight	8 (2.42)	0 (0)	8 (3.42)
Normal	151 (45.62)	14 (14.43)	137 (58.55)
Overweight/obese	172 (51.96)	83 (85.57)	89 (38.03)
WC (cm)	81 (75-88)	88 (85-93)	78.5 (74-84)	< 0.001
Abdominal obesity	116 (35.05)	56 (57.73)	60 (25.64)
SP (mmHg)	109 (100-120.7)	117 (109-130)	105 (98-115)	< 0.001
DP (mmHg)	72 (66-79)	78 (72-85)	69 (64-77)	< 0.001
TC (mg/dL)	208 (183-233)	212 (184-247)	205 (183-230)	0.112
LDL-c (mg/dL)	138 (116-166)	139 (116-165)	138 (116-166)	0.851
TG (mg/dL)	113 (82-182)	180 (133-258)	95 (74-138)	< 0.001
HDL-c (mg/dL)	47 (41-58)	41 (37-45)	51 (44-61)	< 0.001
FPG (mg/dL)	92 (86-99)	98 (93-105)	90 (84-96)	< 0.001
HbA1C (%)	5.5 (5.3-5.7)	5.7 (5.5-5.9)	5.4 (5.2-5.6)	< 0.001
AST (U/L)	19 (16-23)	22 (18-26)	19 (16-22)	< 0.001
ALT (U/L)	20 (15-30)	26 (20-47)	18 (13-24)	< 0.001
GGT (U/L)	30 (18-57)	55 (31-80)	25 (16-39)	< 0.001
White blood cell count (G/L)	6.19 (5.28-7.33)	6.61 (5.56-7.71)	6.07 (5.12-7.07)	0.001
Red blood cell count (T/L)	4.92 (4.52-5.27)	5.10 (4.77-5.37)	4.83 (4.46-5.17)	< 0.001
Platelet (G/L)	259 (225-304)	265 (220-302)	258 (229-304)	0.838
UA (mg/dL)	6.2 (5.1-7.3)	7.2 (6.1-8.5)	5.7 (4.8-6.8)	< 0.001
Creatinine (mg/dL)	0.73 (0.62-0.88)	0.81 (0.69-0.96)	0.69 (0.61-0.83)	< 0.001
Hypertension	26 (7.85)	19 (19.59)	7 (2.99)	< 0.001
Dyslipidemia	305 (92.15)	96 (98.97)	209 (89.32)	0.003
Prediabetes/diabetes	130 (39.27)	64 (65.98)	66 (28.21)	< 0.001
Hyperuricemia	136 (41.09)	63 (64.95)	73 (31.19)	< 0.001
Elevated liver enzymes	95 (28.70)	45 (46.39)	50 (21.37)	< 0.001
MS	71 (21.45)	53 (54.64)	18 (7.69)	< 0.001

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMI: Body mass index; DP: Diastolic pressure; FPG: Fasting plasma glucose; GGT: Gamma-glutamyl transferase; HbA1C: Glycated hemoglobin; HDL-c: High-density lipoprotein cholesterol; LDL-c: Low-density lipoprotein cholesterol; MAFLD: Metabolic dysfunction-associated fatty liver disease; MS: Metabolic syndrome; SP: Systolic pressure; TC: Total cholesterol; TG: Triglyceride; UA: Uric acid; WC: Waist circumference.