Prevalence of metabolic dysfunction-associated fatty liver disease among health check-up attendees: A retrospective study conducted in Vietnam

doi:10.3748/wjg.v31.i37.110797

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Oct 7, 2025 (publication date) through Sep 28, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastroenterol. Oct 7, 2025; 31(37): 110797
Published online Oct 7, 2025. doi: 10.3748/wjg.v31.i37.110797

Prevalence of metabolic dysfunction-associated fatty liver disease among health check-up attendees: A retrospective study conducted in Vietnam

Ngan Lam Lu, Huong Tu Lam, Thong Duy Vo

Ngan Lam Lu, Department of Health Care, Cho Ray Hospital, Ho Chi Minh 72714, Viet Nam

Huong Tu Lam, Thong Duy Vo, Department of Internal Medicine, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh 72714, Viet Nam

Huong Tu Lam, Department of Gastroenterology, Cho Ray Hospital, Ho Chi Minh 72714, Viet Nam

Thong Duy Vo, Department of Gastroenterology, University Medical Center Ho Chi Minh City, Ho Chi Minh 72714, Viet Nam

Co-first authors: Ngan Lam Lu and Huong Tu Lam.

Author contributions: Lu NL and Lam HT prepared the initial draft of the manuscript and made equal contributions as co-first authors; Lu NL and Vo TD contributed to the study conception, design, data collection, and analysis; Lam HT and Vo TD were responsible for reviewing and editing the manuscript; Vo TD supervised the study and provided critical revision of the content; All authors reviewed and approved the final version of the manuscript.

Institutional review board statement: The study was approved by the Ethics Committee of the University of Medicine and Pharmacy at Ho Chi Minh City, No. 836/HDDD-DHYD.

Informed consent statement: Since this was a retrospective study, informed consent was waived.

Conflict-of-interest statement: The authors have no conflicts of interest to declare.

Data sharing statement: No additional data are available.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Thong Duy Vo, MD, PhD, Associate Professor, Dean, Department of Gastroenterology, University Medical Center Ho Chi Minh City, 215 Hong Bang Street, Cho Lon Ward, Ho Chi Minh 72714, Viet Nam. thong.vd@umc.edu.vn

Received: June 16, 2025
Revised: July 4, 2025
Accepted: August 29, 2025
Published online: October 7, 2025
Processing time: 101 Days and 22 Hours

Core Tip

Core Tip: This study investigated the prevalence and associated factors of metabolic dysfunction-associated fatty liver disease (MAFLD) in Vietnamese adults undergoing routine health check-ups. It revealed a high prevalence and significant associations with sex, age, body mass index, and multiple metabolic disorders. These findings highlight the need for early detection and targeted interventions in general populations and support the application of the new MAFLD diagnostic criteria in clinical practice.