Copyright
©The Author(s) 2020.
World J Gastroenterol. Feb 21, 2020; 26(7): 749-758
Published online Feb 21, 2020. doi: 10.3748/wjg.v26.i7.749
Published online Feb 21, 2020. doi: 10.3748/wjg.v26.i7.749
Item | Score | ||
1 | 2 | 3 | |
TBIL, µmol/L | < 34 | 34-51 | > 51 |
ALB, g/L | > 35 | 28-35 | < 28 |
Prothrombin time prolongation, s | < 4 | 4-6 | > 6 |
PA for males, mg/L | > 190 | 130-190 | < 130 |
PA for females, mg/L | > 170 | 120-170 | < 120 |
Variable | All patients (n = 204) |
Sex (male/female) | 174/30 |
Age, yr | 52.0 ± 11.4 |
BMI, kg/m2 | 23.2 ± 3.6 |
Cause of hepatitis (Hepatitis B/C/Others) | 174/2/28 |
PH (yes/no) | 48/156 |
Liver cirrhosis (yes/no) | 120/84 |
P grade (A/B) | 187/17 |
BCLC stage (0 or A/B/C) | 113/62/29 |
PA, mg/L | 198.5 (149.3-238.0) |
ALB, g/L | 41.0 ± 4.7 |
TBIL, μmol/L | 13.3 (9.7-18.3) |
PT, s | 13.7 (13.0-14.5) |
ALT, U/L | 36.0 (26.3-56.0) |
AFP, μg/L | 76.4 (9.02-1082.5) |
INR | 1.0 (0.98-1.1) |
PLT, × 109/L | 135.0 (99.8-181.0) |
Number of tumors (1/2/≥3) | 161/27/16 |
Tumor size, cm | 4.0 (3.0-6.5) |
PVTT (yes/no) | 30/174 |
Capsule formation (yes/no) | 27/177 |
Differentiation (well/poor) | 81/123 |
Surgical bleeding, mL | 300 (180-575) |
Blood transfusion (yes/no) | 68/136 |
Type of liver resection (minor/major) | 159/45 |
Intraoperative radiotherapy and/or chemotherapy (yes/no) | 148/56 |
ALBI grade (1/2/3) | 136/66/2 |
MCP grade (1/2/3) | 110/52/42 |
Overall survival time, mo | 44.0 (22.0-74.0) |
Recurrence-free survival time, mo | 22.0 (5.0-45.0) |
Variables | Overall survival | Recurrence-free survival | ||||
Univariate | Multivariate | Univariate | Multivariate | |||
P value | HR (95%CI) | P value | P value | HR (95%CI) | P value | |
Sex (M/F) | 0.595 | 0.962 | ||||
Age (> 50/< 50 yr) | 0.020 | 1.853 (1.243-2.761) | 0.002 | 0.071 | ||
BMI (≥ 24/<24 kg/m2) | 0.596 | 0.770 | ||||
Cause of hepatitis (HBV/HCV/others) | 0.269 | 0.422 | ||||
ALT (> 40/≤ 40 U/L) | 0.255 | 0.069 | ||||
AFP (≥ 400/< 400 μg/L) | 0.111 | 0.092 | ||||
INR (≥ 1.3/< 1.3) | < 0.001 | 0.009 | ||||
PLT (≥ 100/< 100 × 109/L) | 0.392 | 0.713 | ||||
Number of tumors (single/≥ 2) | 0.243 | 0.065 | ||||
Tumor size (≥ 5/< 5 cm) | < 0.001 | < 0.001 | ||||
Blood transfusion (yes/no) | 0.001 | 0.003 | ||||
Surgical bleeding (> 400/≤ 400 mL) | 0.005 | 0.003 | 1.437 (1.004-2.058) | 0.048 | ||
Types of liver resection (minor/major) | < 0.001 | < 0.001 | ||||
Intraoperative radiotherapy and/or chemotherapy (yes/no) | 0.649 | 0.430 | ||||
PVTT (yes/no) | < 0.001 | 0.005 | ||||
Capsule formation (yes/no) | 0.408 | 0.374 | ||||
Differentiation (good/poor) | 0.004 | 2.230 (1.452-3.426) | < 0.001 | 0.029 | ||
PH (yes/no) | 0.809 | 0.542 | ||||
Liver cirrhosis (yes/no) | 0.944 | 0.896 | ||||
Child-Pugh grade (A/B) | < 0.001 | 0.001 | ||||
BCLC stage (0 or A/B/C) | < 0.001 | < 0.001 | ||||
0 or A | 1 | 1 | ||||
B | 2.635 (1.235-5.622) | 0.012 | 2.246 (1.095-4.607) | 0.027 | ||
ALBI grade (1/2/3) | < 0.001 | 0.003 | ||||
MCP grade | < 0.001 | < 0.001 | ||||
1 | 1 | 1 | ||||
2 | 1.864 (1.174-2.959) | 0.008 | 1.830 (1.246-2.687) | 0.002 | ||
3 | 2.005 (1.071-3.753) | 0.030 |
- Citation: Huang F, Gao J. Modified Child-Pugh grade vs albumin-bilirubin grade for predicting prognosis of hepatocellular carcinoma patients after hepatectomy. World J Gastroenterol 2020; 26(7): 749-758
- URL: https://www.wjgnet.com/1007-9327/full/v26/i7/749.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i7.749