Retrospective Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 21, 2020; 26(7): 749-758
Published online Feb 21, 2020. doi: 10.3748/wjg.v26.i7.749
Modified Child-Pugh grade vs albumin-bilirubin grade for predicting prognosis of hepatocellular carcinoma patients after hepatectomy
Feng Huang, Jian Gao
Feng Huang, Second Clinical College, Chongqing Medical University, Chongqing 400010, China
Jian Gao, Department of Gastroenterology, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China
Author contributions: Huang F conceptualized and designed the study, acquired, analysed, and interpreted the data, and drafted the manuscript; Gao J conceptualized and designed the study, and critically revised the manuscript for important intellectual content; all authors approved the final version of the manuscript.
Supported by National Natural Science Foundation of China, No. 81572888.
Institutional review board statement: The study was reviewed and approved by the ethics committee of the Second Affiliated Hospital of Chongqing Medical University (No. 2018-025).
Informed consent statement: All study participants gave their informed consent prior to study enrollment (by written or verbal).
Conflict-of-interest statement: None declared.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jian Gao, PhD, Professor, Chief Doctor, Department of Gastroenterology, Second Affiliated Hospital, Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing 400010, China. 982213482@qq.com
Received: November 28, 2019
Peer-review started: November 28, 2019
First decision: December 28, 2019
Revised: January 7, 2020
Accepted: January 11, 2020
Article in press: January 11, 2020
Published online: February 21, 2020
Processing time: 84 Days and 8.9 Hours
Core Tip

Core tip: We discovered that only a few studies have evaluated the predictive power of prealbumin-involving modified Child-Pugh (MCP) grade for the prognosis of patients with hepatocellular carcinoma (HCC). The objective, recognizable, and simple method, the albumin-bilirubin (ALBI) grade, for predicting the long-term prognosis of HCC patients has been widely proven in the international environment. In this study, receiver operating characteristics curve analysis showed that the MCP grade had higher accuracy than the ALBI grade, and the area under the curve of the MCP grade was larger than that of the ALBI grade. The MCP grade may be the best tool for the selection of HCC treatment strategies.