Relationship between antral distension and postprandial symptoms in functional dyspepsia

Table 1 Major demographic characteristics of investigated subjects

	Healthy controls	FD patients	P
	(n = 21)	(n = 94)
Age median (IQR) yr	27 (26-29)	42 (31-52)	< 0.001
BMI median (IQR) kg/m2	22.4 (20-23)	22.0 (19.8-25.0)	0.47
Female (%)	13 (61.9%)	62 (66.0%)	0.72

IQR: Interquartile range.

Table 2 Percentage of FD patients with symptoms at each time interval evaluated

Time (min)	Pain (%)	Fullness (%)	Bloating (%)	Nausea (%)	Belching (%)	Burning (%)	Headache (%)	Drowsiness (%)	Any (%)
0	1	13.8	9.6	3.2	10.6	0	0	2.1	26.6
30	3.2	22.3	12.8	4.3	18	1	2.1	7.5	44.7
60	6.4	24.5	14.9	5.3	22.3	2.1	3.2	13.8	54.3
120	6.4	24.5	14.9	5.3	24.5	3.2	3.2	13.8	54.3
180	4.3	20.2	12.8	5.3	20.2	3.2	3.2	17	48.9
240	3.2	14.9	10.6	5.3	18	3.2	4.3	15.9	43.6
300	2	12.8	9.6	5.3	15.9	2.1	2.1	12.8	38.3
At least once	7.4	28.7	14.9	7.4	26.6	3.2	5.3	18	58.5

Table 3 AOR with 95% CI of having GI and extra-GI symptoms on the basis of antral volume variations

	Current AV			Previous AV			Delta AV			Mean weighted AV			Maximal AV
	(per 10 mL unit increase)			(per 10 mL unit increase)			(per 10 mL unit increase)			(per 10 mL unit increase)			(per 10 mL unit increase)
Symptom	AOR	95% CI	P	AOR	95% CI	P	AOR	95% CI	P	AOR	95% CI	P	AOR	95%CI	P
Pain	0.96	0.79-1.18	0.72	0.96	0.78-1.17	0.67	1.03	0.93-1.14	0.54	0.94	0.67-1.31	0.72	0.9	0.69-1.19	0.49
Fullness	0.99	0.84-1.17	0.97	0.98	0.82-1.18	0.88	1	0.95-1.06	0.82	0.95	0.73-1.25	0.74	0.97	0.83-1.13	0.68
Bloating	1.21	0.98-1.49	0.07	1.22	0.98-1.51	0.06	0.99	0.93-1.05	0.7	1.37	0.99-1.89	0.05	1.21	0.99-1.48	0.06
Nausea	0.99	0.76-1.3	0.98	1.06	0.8-1.4	0.67	0.84	0.7-1	0.05	1.18	0.82-1.69	0.37	1.17	0.94-1.44	0.15
Burning	0.87	0.55-1.38	0.57	0.81	0.39-1.67	0.58	1.1	0.87-1.39	0.39	0.68	0.2-2.25	0.53	0.64	0.17-2.33	0.5
Belching	1	0.84-1.19	0.95	0.96	0.78-1.17	0.67	1.07	1.01-1.12	0.008	0.94	0.69-1.27	0.69	0.98	0.82-1.17	0.81
Headache	1.04	0.77-1.4	0.79	1	0.77-1.31	0.96	1.03	0.88-1.2	0.69	0.9	0.58-1.43	0.68	0.93	0.7-1.23	0.64
Drowsiness	1.42	1.16-1.73	0.001	1.33	1.08-1.65	0.007	1.12	1.06-1.19	0.001	1.46	1.05-2.01	0.02	1.26	1.03-1.53	0.02
Palpitation	1	0.72-1.4	0.96	0.99	0.71-1.38	0.97	0.98	0.9-1.06	0.67	0.89	0.49-1.62	0.7	0.93	0.65-1.32	0.68
Any symptom	1.13	0.97-1.31	0.12	1.1	0.94-1.3	0.24	1.03	0.99-1.08	0.11	1.15	0.9-1.46	0.25	1.11	0.95-1.29	0.18

Table 4 AOR with 95% CI of having delayed gastric emptying on the basis of symptoms, fasting antral volume (FAV) and BMI

	AOR	95% CI	P
Drowsiness	3.59	1.12-11.54	0.03
Fasting antral volume1	1.09	1.02-1.17	0.007

AOR: Adjusted odds ratio;

¹AOR estimated per 5 mL increase (e.g. FAV of 20 mL vs 15 mL).