Lou G, Gao Y, Ning XM, Zhang QF. Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor. World J Gastroenterol 2005; 11(32): 5032-5036 [PMID: 16124061 DOI: 10.3748/wjg.v11.i32.5032]
Corresponding Author of This Article
Ge Lou, Department of Gynecology, Tumor Hospital of Harbin Medical University, Harbin 150040, Heilongjiang Province, China. dr-lg911@163.com
Article-Type of This Article
Brief Reports
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Aug 28, 2005; 11(32): 5032-5036 Published online Aug 28, 2005. doi: 10.3748/wjg.v11.i32.5032
Table 1 Expression of CD44v6, VEGF, MMP-2, and MMP-9 in epithelial ovarian carcinoma, Krukenberg tumor, and gastric carcinoma
CD44v6
VEGF
MMP-2
MMP-9
n
n
%
n
%
n
%
n
%
Normal ovarian tissue
20
2
10.0
1
5.0
–
–
Epithelial ovarian cancer
45
16
35.6
14
31.1
8
17.8
6
13.3
Serous adenocarcinoma
15
6
40.0
7
46.7
4
26.7
3
20.0
Mucous adenocarcinoma
16
4
25.0
3
18.8
2
12.5
2
12.5
Other types
14
6
42.9
4
28.6
2
14.3
1
7.1
Krukenberg tumor
38
27
71.1
27
71.1
31
81.6
31
81.6
Moderate differentiation
14
9
64.3
10
71.4
12
85.6
10
71.4
Poor differentiation
24
18
75.0
17
70.8
19
79.2
21
87.5
Gastric carcinoma
38
30
78.9
27
73.7
25
65.8
23
60.5
High and moderate differentiation
16
12
75.0
9
56.3
7
31.8
6
37.5
Poor differentiation
22
18
81.8
16
72.7
18
81.8
17
77.3
Table 2 Relation between expressions of CD44v6, VEGF, MMP-2, and MMP-9 in Krukenberg tumor
CD44v6
MMP-2
MMP-9
r
P
r
P
r
P
VEGF
0.342
0.023
0.498
0.000
0.498
0.000
CD44v6
0.419
0.005
0.213
0.212
MMP-2
0.488
0.001
Table 3 Relation between expressions of CD44v6, VEGF, MMP-2, and MMP-9 in primary epithelial ovarian carcinoma
CD44v6
MMP-2
MMP-9
r
P
r
P
r
P
VEGF
0.605
0.004
0.608
0.003
0.711
0
CD44v6
0.684
0.001
0.804
0
MMP-2
0.457
0.037
Table 4 Relation between expressions of CD44v6, VEGF, MMP-2, and MMP-9 in primary gastric carcinoma
CD44v6
MMP-2
MMP-9
r
P
r
P
r
P
VEGF
0.366
0.046
0.25
0.378
0.385
0.035
CD44v6
0.46
0.011
0.200
0.475
MMP-2
0.439
0.015
Citation: Lou G, Gao Y, Ning XM, Zhang QF. Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor. World J Gastroenterol 2005; 11(32): 5032-5036