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Contents Volume 31 Issue 11 March 21, 2025

Editorial

Radiomics and clinicoradiological factors as a promising approach for predicting microvascular invasion in hepatitis B-related hepatocellular carcinoma

Weronika Kruczkowska, Julia Gałęziewska, Mateusz Kciuk, Żaneta Kałuzińska-Kołat, Lin-Yong Zhao, Damian Kołat

World J Gastroenterol 31(11):101903. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.101903

Abstract (435) | Core Tip (431) | Full Article (HTML) (1765) | Full Article (PDF)-368K (140) | Full Article with Cover (PDF)-621K (140) | Full Article (XML)-56K (104) | Audio-407K (26) | Peer-Review Report-316K (88) | Answering Reviewers-366K (94) | Received: 09/30/2024 | Revised: 01/29/2025 | Accepted: 02/12/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (4375) | Similar Articles (1938) | Timeline of Article Publication (6) | Article Quality Tracking (0) | Cite |

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Phospholipase D2: A biomarker for stratifying disease severity in acute pancreatitis?

Bin Wang, Min Xia, Yi-Fan Zhao, Ntim Michael, Yun Teng, Jia-Hui Lv, Zhi-Hui Wang

World J Gastroenterol 31(11):104033. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.104033

Abstract (556) | Core Tip (510) | Full Article (HTML) (2808) | Figures (1-1) (352) | Tables (1-1) (371) | Full Article (PDF)-798K (165) | Full Article with Cover (PDF)-1048K (217) | Full Article (XML)-108K (133) | Audio-1024K (32) | Peer-Review Report-312K (112) | Answering Reviewers-178K (99) | Received: 12/07/2024 | Revised: 02/03/2025 | Accepted: 02/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (7344) | Similar Articles (320) | Timeline of Article Publication (6) | Authors Evaluation (8) | Article Quality Tracking (0) | Reader Comments (1) | Cite |

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Review

Cholangiocarcinoma: The era of liquid biopsy

Evgenia Kotsifa, Francesca Saffioti, Vasileios K Mavroeidis

World J Gastroenterol 31(11):104170. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.104170

Abstract (474) | Core Tip (552) | Full Article (HTML) (4415) | Figures (1-2) (363) | Tables (1-1) (365) | Full Article (PDF)-9633K (286) | Full Article with Cover (PDF)-9880K (169) | Full Article (XML)-373K (130) | Audio-1561K (68) | Peer-Review Report-230K (102) | Answering Reviewers-101K (91) | Received: 12/11/2024 | Revised: 01/28/2025 | Accepted: 02/14/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (9042) | Similar Articles (171) | Timeline of Article Publication (10) | Authors Evaluation (8) | Article Quality Tracking (1) | Cite |

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Retrospective Cohort Study

Preoperative prediction of textbook outcome in intrahepatic cholangiocarcinoma by interpretable machine learning: A multicenter cohort study

Yong-Yi Zeng, Shi-Chuan Tang, Ke-Can Lin, Jing-Dong Li, Wei-Ping Zhou, Rui-Lin Fan, Qi-Zhu Lin, Jiang-Tao Li, Hong-Zhi Liu, Luo-Bin Guo, Cong Luo, Ting-Feng Huang

World J Gastroenterol 31(11):100911. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.100911

Abstract (452) | Core Tip (516) | Full Article (HTML) (2226) | Figures (1-6) (334) | Tables (1-3) (356) | Full Article (PDF)-1831K (194) | Full Article with Cover (PDF)-2079K (271) | Full Article (XML)-146K (95) | Audio-301K (36) | Peer-Review Report-262K (97) | Answering Reviewers-548K (108) | Received: 08/30/2024 | Revised: 01/10/2025 | Accepted: 02/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (12) | Total Visits (6492) | Similar Articles (87) | Timeline of Article Publication (9) | Authors Evaluation (5) | Article Quality Tracking (1) | Reader Comments (2) | Cite |

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Retrospective Study

Construction and validation of machine learning-based predictive model for colorectal polyp recurrence one year after endoscopic mucosal resection

Yi-Heng Shi, Jun-Liang Liu, Cong-Cong Cheng, Wen-Ling Li, Han Sun, Xi-Liang Zhou, Hong Wei, Su-Juan Fei

World J Gastroenterol 31(11):102387. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.102387

Abstract (586) | Core Tip (573) | Full Article (HTML) (2728) | Figures (1-5) (398) | Tables (1-3) (357) | Full Article (PDF)-2406K (206) | Full Article with Cover (PDF)-2653K (1807) | Full Article (XML)-193K (109) | Audio-440K (30) | Peer-Review Report-261K (97) | Answering Reviewers-308K (100) | Supplementary Material-386K (101) | Received: 10/16/2024 | Revised: 01/25/2025 | Accepted: 02/14/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (9722) | Similar Articles (139) | Timeline of Article Publication (12) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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Development and validation of a predictive model for the pathological upgrading of gastric low-grade intraepithelial neoplasia

Kun-Ming Lyu, Qian-Qian Chen, Yi-Fan Xu, Yao-Qian Yuan, Jia-Feng Wang, En-Qiang Ling-Hu, Jun Wan

World J Gastroenterol 31(11):104377. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.104377

Abstract (431) | Core Tip (405) | Full Article (HTML) (1357) | Figures (1-7) (331) | Tables (1-2) (341) | Full Article (PDF)-2655K (168) | Full Article with Cover (PDF)-2904K (156) | Full Article (XML)-99K (99) | Audio-288K (14) | Peer-Review Report-195K (87) | Answering Reviewers-230K (89) | Received: 12/20/2024 | Revised: 01/17/2025 | Accepted: 02/11/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (5278) | Similar Articles (1) | Timeline of Article Publication (12) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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Observational Study

Role of transient elastography in the diagnosis and prognosis of Fontan-associated liver disease

Marta Cuadros, Marta Abadía, Pilar Castillo, María Dolores Martín-Arranz, Nerea Gonzalo, Miriam Romero, Araceli García-Sánchez, Javier García-Samaniego, Antonio Olveira, José Ruiz-Cantador, Óscar González-Fernández, Inés Ponz, Pablo Merás, Carlos Merino, Adriana Rodríguez-Chaverri, Enrique Balbacid, Consuelo Froilán

World J Gastroenterol 31(11):103178. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.103178

Abstract (416) | Core Tip (444) | Full Article (HTML) (1951) | Figures (1-2) (336) | Tables (1-8) (314) | Full Article (PDF)-540K (180) | Full Article with Cover (PDF)-788K (156) | Full Article (XML)-136K (91) | Audio-528K (16) | Peer-Review Report-205K (85) | Answering Reviewers-85K (97) | Received: 11/10/2024 | Revised: 01/12/2025 | Accepted: 02/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (6) | Total Visits (5689) | Similar Articles (30) | Timeline of Article Publication (5) | Article Quality Tracking (0) | Cite |

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Prospective Study

Attenuation imaging for hepatic steatosis in chronic hepatitis B vs metabolic dysfunction-associated steatotic liver disease

Hong Ding, Masatoshi Kudo, Yi Cheng, Li-Yun Xue, Jing Liang, Xian-Jue Huang, Iwaki Akiyama, Guang-Wen Cheng, Xue-Qi Li

World J Gastroenterol 31(11):102795. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.102795

Abstract (509) | Core Tip (509) | Full Article (HTML) (1530) | Figures (1-6) (382) | Tables (1-4) (357) | Full Article (PDF)-2402K (217) | Full Article with Cover (PDF)-2654K (243) | Full Article (XML)-104K (125) | Audio-92K (26) | Peer-Review Report-267K (112) | Answering Reviewers-254K (102) | Supplementary Material-85K (99) | Received: 11/04/2024 | Revised: 01/25/2025 | Accepted: 02/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (5927) | Similar Articles (274) | Timeline of Article Publication (3) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Basic Study

NMDAR2B/PKA/CREB signaling pathway contributes to esophageal neuropathic pain in gastroesophageal reflux disease

Yi Wang, Guan-Wu Li, Sheng-Liang Zhu, Ting-Ting Xu, Yi-Wen Qin, Chuan-Qi Cheng, Qin-Wei Zheng, Cong He, Bing-Duo Zhou, Sheng-Quan Fang

World J Gastroenterol 31(11):98974. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.98974

Abstract (372) | Core Tip (435) | Full Article (HTML) (1702) | Figures (1-13) (329) | Tables (1-3) (360) | Full Article (PDF)-22087K (156) | Full Article with Cover (PDF)-22337K (144) | Full Article (XML)-115K (101) | Audio-470K (24) | Peer-Review Report-291K (98) | Answering Reviewers-256K (98) | Supplementary Material-69K (96) | Received: 07/10/2024 | Revised: 12/10/2024 | Accepted: 02/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (5559) | Similar Articles (111) | Timeline of Article Publication (7) | Article Quality Tracking (0) | Cite |

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NAD+/SIRT1 pathway regulates glycolysis to promote oxaliplatin resistance in colorectal cancer

Ya-Ru Niu, Mi-Dan Xiang, Wen-Wei Yang, Yu-Ting Fang, Hai-Li Qian, Yong-Kun Sun

World J Gastroenterol 31(11):100785. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.100785

Abstract (424) | Core Tip (458) | Full Article (HTML) (2709) | Figures (1-8) (383) | Full Article (PDF)-13853K (202) | Full Article with Cover (PDF)-14103K (161) | Full Article (XML)-169K (136) | Audio-303K (39) | Peer-Review Report-244K (104) | Answering Reviewers-180K (105) | Received: 08/26/2024 | Revised: 12/13/2024 | Accepted: 02/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (7351) | Similar Articles (1155) | Timeline of Article Publication (5) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Apatinib regulates the glycolysis of vascular endothelial cells through PI3K/AKT/PFKFB3 pathway in hepatocellular carcinoma

Yi Wu, Bin-Bin Xie, Bing-Liang Zhang, Qing-Xin Zhuang, Shi-Wei Liu, Hong-Ming Pan

World J Gastroenterol 31(11):102848. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.102848

Abstract (382) | Core Tip (386) | Full Article (HTML) (1874) | Figures (1-8) (345) | Full Article (PDF)-21548K (157) | Full Article with Cover (PDF)-21800K (165) | Full Article (XML)-138K (94) | Audio-2773K (22) | Peer-Review Report-228K (90) | Answering Reviewers-421K (87) | Supplementary Material-630K (95) | Received: 11/06/2024 | Revised: 01/17/2025 | Accepted: 02/11/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (6881) | Similar Articles (1897) | Timeline of Article Publication (5) | Article Quality Tracking (0) | Cite |

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Inhibition of the SERPINB5/HSP90AA1 axis restrains the proliferation and invasion of rectal cancer

Ze-Song Meng, Ji-Tao Hu, Hao Wu, Bao-Kun Li

World J Gastroenterol 31(11):103412. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.103412

Abstract (389) | Core Tip (410) | Full Article (HTML) (1488) | Figures (1-6) (380) | Full Article (PDF)-20777K (185) | Full Article with Cover (PDF)-21029K (153) | Full Article (XML)-90K (96) | Audio-224K (12) | Peer-Review Report-194K (97) | Answering Reviewers-234K (112) | Received: 11/26/2024 | Revised: 01/10/2025 | Accepted: 02/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (5092) | Similar Articles (349) | Timeline of Article Publication (4) | Article Quality Tracking (0) | Reader Comments (1) | Cite |

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Trichostatin A augments cell migration and epithelial-mesenchymal transition in esophageal squamous cell carcinoma through BRD4/c-Myc endoplasmic reticulum-stress pathway

Yan-Min Chen, Wen-Qian Yang, Ying-Ying Fan, Zhi Chen, Yu-Zhen Liu, Bao-Sheng Zhao

World J Gastroenterol 31(11):103449. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.103449

Abstract (430) | Core Tip (483) | Full Article (HTML) (1722) | Figures (1-7) (344) | Tables (1-2) (339) | Full Article (PDF)-284260K (198) | Full Article with Cover (PDF)-284510K (203) | Full Article (XML)-171K (104) | Audio-1066K (12) | Peer-Review Report-213K (94) | Answering Reviewers-149K (84) | Supplementary Material-245K (111) | Received: 11/22/2024 | Revised: 01/09/2025 | Accepted: 02/14/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (5923) | Similar Articles (154) | Timeline of Article Publication (5) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Meta-Analysis

Changes in Intestinal flora is associated with chronic diseases

Guo-Heng Jiang, Hong-Yu Li, Lin-Jun Xie, Jing-Yuan Fan, Shi-Yi Li, Wen-Qian Yu, Yi-Ting Xu, Meng-Lin He, Yi Jiang, Xuan Bai, Jin Zhou, Xin Wang

World J Gastroenterol 31(11):103507. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.103507

Abstract (470) | Core Tip (401) | Full Article (HTML) (2584) | Figures (1-4) (351) | Full Article (PDF)-11220K (214) | Full Article with Cover (PDF)-11465K (246) | Full Article (XML)-220K (98) | Audio-174K (21) | Peer-Review Report-222K (105) | Answering Reviewers-162K (98) | Supplementary Material-99K (102) | Received: 11/21/2024 | Revised: 12/26/2024 | Accepted: 02/24/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (6085) | Similar Articles (7) | Timeline of Article Publication (10) | Authors Evaluation (6) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

Roles of autophagy and long non-coding RNAs in gastric cancer

Thang Viet Luong, Mai Thi Thu Cao, Nam Van Duc Nguyen, Hai Nguyen Ngoc Dang, Trung Tran Nguyen

World J Gastroenterol 31(11):101124. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.101124

Abstract (465) | Core Tip (435) | Full Article (HTML) (1827) | Figures (1-1) (326) | Full Article (PDF)-1683K (172) | Full Article with Cover (PDF)-1932K (186) | Full Article (XML)-110K (93) | Audio-193K (30) | Peer-Review Report-219K (95) | Answering Reviewers-78K (102) | Received: 09/05/2024 | Revised: 01/24/2025 | Accepted: 02/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (4966) | Similar Articles (1393) | Timeline of Article Publication (4) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Validity of the efficacy of the spray flushing cleaning method in flexible endoscope reprocessing

Sameera Zeehan Anwardeen Ziaudeen, Charleen Shanwen Yeo, Danson Xue Wei Yeo

World J Gastroenterol 31(11):101743. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.101743

Abstract (400) | Core Tip (427) | Full Article (HTML) (1278) | Tables (1-1) (337) | Full Article (PDF)-363K (151) | Full Article with Cover (PDF)-615K (113) | Full Article (XML)-46K (84) | Audio-445K (11) | Peer-Review Report-441K (89) | Answering Reviewers-43K (93) | Received: 09/25/2024 | Revised: 02/05/2025 | Accepted: 02/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (4009) | Similar Articles (5) | Timeline of Article Publication (4) | Article Quality Tracking (0) | Cite |

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Improving radiomics-based models for esophagogastric variceal bleeding risk prediction in cirrhotic patients

Arunkumar Krishnan

World J Gastroenterol 31(11):101804. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.101804

Abstract (404) | Core Tip (422) | Full Article (HTML) (1267) | Full Article (PDF)-361K (137) | Full Article with Cover (PDF)-614K (129) | Full Article (XML)-39K (92) | Audio-1787K (10) | Peer-Review Report-281K (98) | Answering Reviewers-93K (88) | Received: 09/26/2024 | Revised: 01/22/2025 | Accepted: 02/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3719) | Similar Articles (140) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Impact of poorly controlled type II diabetes mellitus on chemoresistance in colorectal cancer

Aditya Gaur, Rick Maity, Arkadeep Dhali, Jyotirmoy Biswas

World J Gastroenterol 31(11):104065. Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.104065

Abstract (418) | Core Tip (421) | Full Article (HTML) (2219) | Tables (1-1) (357) | Full Article (PDF)-381K (138) | Full Article with Cover (PDF)-632K (140) | Full Article (XML)-83K (91) | Audio-1238K (17) | Peer-Review Report-269K (94) | Answering Reviewers-126K (92) | Received: 12/08/2024 | Revised: 01/16/2025 | Accepted: 02/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (5120) | Similar Articles (1634) | Timeline of Article Publication (3) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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