Virulence and potential pathogenicity of coccoid Helicobacter pylori induced by antibiotics

Figure 1 Invasion of coccoid H. pylori into Hep-2 cell. Transmission electron microscope, × 15 000

Figure 2 A. SDS-PAGE pattern of whole cell proteins of H. pylori, B. Western blot pattern of the proteins of H. pylori. a. marker; b.d.f. spiral forms of H.pyloriF₄₄, F₄₅ and F₄₉, respectively; c.e.g. coccoid forms of H.pylori F₄₄, F₄₅ and F₄₉, respectively.

Figure 3 The results of PCR of H. pylori F₄₄. a. PCR marker 100bp lader; b.c. ureA gene; d.e. ureB gene; f.g. hpaA gene; h.i. vacA gene; j.k. cagA gene; b.d.f.h.j. spiral forms of H.pylori; c.e.g.i.k. coccoid forms of H.pylori.

Figure 4 The pattern of PCR-SSCP of H. pylori F₄₄. a.b. vacA gene; c.d. ureA gene; e.f. cagA gene; g.h. hpaA gene; a.c.e.g. spiral forms of H. pylori; b.d.f.h. coccoid forms of H.pylori.