Application of intraoperative laparoscopic ultrasound guidance combined with Sonazoid contrast in surgical treatment of colorectal liver metastasis

Figure 1 Images of the target lesion in gray-scale ultrasound phase and S-contrast enhanced ultrasound Kupffer phase or arterial phase. A: The target lesion (indicated by arrow) is isoechoic and invisible in the gray-scale ultrasound (GEUS) phase, but demonstrates good visibility in the S-contrast-enhanced ultrasound (S-CEUS) Kupffer phase; B: The target lesion is isoechoic and invisible in GEUS phase, but demonstrates good visibility in the S-CEUS arterial phase; C: The target lesion is < 1 cm in size, isoechoic, and invisible in the GEUS phase, but demonstrates good visibility in the S-CEUS arterial phase; D: The target lesion is < 1 cm in size, isoechoic, and invisible in the GEUS phase, but demonstrates good visibility in the S-CEUS Kupffer phase.

Figure 2 Target lesion scores across phases. GEUS: Gray-scale ultrasound; S-CEUS: S-contrast-enhanced ultrasound.