Egypt’s metabolic dysfunction associated steatotic liver disease: Genetic and dietary nexus, shaping artificial intelligence driven healthier future

Figure 1 Comparison of correlation indices between patients and healthy controls. A: Prevalence of various body mass index and waist circumference categories among participants diagnosed with metabolically dysfunction-associated steatotic liver disease compared to healthy controls; B: Walking and exercise habits among participants with metabolically dysfunction-associated steatotic liver disease and healthy controls. MASLD: Metabolically dysfunction-associated steatotic liver disease.

Figure 2 Prevalence and percentage distribution of various clinical characteristics, laboratory values, and genetic markers among the study participants. HbA1c: Glycated hemoglobin; HDL: High-density lipoprotein; HOMA-IR: Homeostasis Model Assessment of Insulin Resistance; LDL: Low-density lipoproteins; TGs: Triglycerides.

Figure 3 Vibration-controlled transient elastography. A: Distribution across different categories of FibroScan (F), controlled attenuation parameter (S) dB/m, and kilopascals; B: Mean and SD of controlled attenuation parameter and kilopascals among participants with metabolic syndrome and those without. CAP: Controlled attenuation parameter; KPA: Kilopascals; MASLD: Metabolically dysfunction-associated steatotic liver disease.

Figure 4 Dietary energy consumption among participants with metabolically dysfunction-associated steatotic liver disease and healthy controls. MASLD: Metabolically dysfunction-associated steatotic liver disease; MUFA: Monounsaturated fatty acid; PUFA: Polyunsaturated fatty acid.

Figure 5 A heatmap visualizing correlation coefficients (r) between various clinical factors and two measurement methods: Controlled attenuation parameter and kilopascals. ^aP < 0.05. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMI: Body mass index; CRP: C-reactive protein; FT: Free thyroxine; γGT: Gamma-glutamyl transferase; HbA1c: Glycated hemoglobin; HDL: High-density lipoprotein; HOMA-IR: Homeostasis Model Assessment of Insulin Resistance; LDL: Low-density lipoproteins; LPL: Lipoprotein lipase; MUFA: Monounsaturated fatty acid; PUFA: Polyunsaturated fatty acid; TSH: Thyrotropin; VLDL: Very low-density lipoproteins.