©Author(s) (or their employer(s)) 2026.
World J Gastroenterol. Mar 14, 2026; 32(10): 115130
Published online Mar 14, 2026. doi: 10.3748/wjg.v32.i10.115130
Published online Mar 14, 2026. doi: 10.3748/wjg.v32.i10.115130
Figure 1 Immunoperoxidase staining for macrophages in adjacent nontumor mucosa and tumor center of primary colorectal cancer.
A-D: Adjacent nontumor mucosa; E-H: Tumor center of primary colorectal cancer.
Figure 2 Statistics depicting the spatial distribution of macrophages in adjacent nontumor mucosa and tumor center.
A: Stage I-III; B: Stage IV. Statistics depicting the spatial distribution of CD68+, CD163+, CD206+ and CD80+ tumor infiltrating macrophages per mm2 of the section in the adjacent nontumor mucosa and tumor center of primary colorectal cancer in patients of stage I-III and IV. Black lines: Medians. aP < 0.05, cP < 0.001. NM: Adjacent nontumor mucosa; TC: Tumor center.
Figure 3 Kaplan-Meier analysis for overall survival according to high vs low densities of macrophages in adjacent nontumor mucosa.
A: Stage I-III; B: Stage IV. Kaplan-Meier analysis for overall survival according to high vs low densities of CD80+ macrophages in adjacent nontumor mucosa in stage I-III patients and CD163+ macrophages in adjacent nontumor mucosa in stage IV patients.
- Citation: Ye WJ, Ali E, Pavlov S, Červenková L, Ambrozkiewicz F, Vyčítal O, Hošek P, Zitrický F, Daum O, Liška V, Hemminki K, Trailin A. Distribution and prognostic value of macrophages in colorectal cancer and adjacent mucosa in patient stages I-III vs IV. World J Gastroenterol 2026; 32(10): 115130
- URL: https://www.wjgnet.com/1007-9327/full/v32/i10/115130.htm
- DOI: https://dx.doi.org/10.3748/wjg.v32.i10.115130