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©The Author(s) 2025.
World J Gastroenterol. Dec 7, 2025; 31(45): 112926
Published online Dec 7, 2025. doi: 10.3748/wjg.v31.i45.112926
Published online Dec 7, 2025. doi: 10.3748/wjg.v31.i45.112926
Figure 1 Study design and flow chart.
PFIA: Pediatric fistula-in-ano; WBC: White blood cell; NEUT: Neutrophil; LYMPH: Lymphocyte; MONO: Monocyte; EO: Eosinophil; BASO: Basophil; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio; SII: Systemic immune-inflammation index; SIRI: Systemic inflammatory response index.
Figure 2 Mantel’s test and logistic regression model.
PFIA: Pediatric fistula-in-ano; WBC: White blood cell; NEUT: Neutrophil; LYMPH: Lymphocyte; MONO: Monocyte; EO: Eosinophil; BASO: Basophil; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio; SII: Systemic immune-inflammation index; SIRI: Systemic inflammatory response index.
Figure 3 Subgroup analysis of exposure factors and perianal abscesses outcomes according to age and sex.
OR: Odds ratio; CI: Confidence interval; WBC: White blood cell; NEUT: Neutrophil; LYMPH: Lymphocyte; MONO: Monocyte; EO: Eosinophil; BASO: Basophil; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio; SII: Systemic immune-inflammation index; SIRI: Systemic inflammatory response index.
Figure 4 Complete blood count index and derived inflammatory biomarkers predict the clinical efficacy and clinical value of pediatric fistula-in-ano.
A: Receiver operating characteristic curve analysis of pediatric fistula-in-ano (PFIA) on complete blood count; B: Decision curve analysis (DCA) of complete blood count (CBC) derivative index by PFIA; C: DCA of PFIA on complete blood count; D: DCA of CBC derivative index by PFIA. AUC: Area under the curve; WBC: White blood cell; NEUT: Neutrophil; LYMPH: Lymphocyte; MONO: Monocyte; EO: Eosinophil; BASO: Basophil; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio; SII: Systemic immune-inflammation index; SIRI: Systemic inflammatory response index.
- Citation: Ma HF, Chen YH, Wang Y, Zhang XC, Li JN, Wang YM, Zhou ZY. Complete blood counts and their derived inflammatory markers with anal fistulas in male children: A retrospective case-control study. World J Gastroenterol 2025; 31(45): 112926
- URL: https://www.wjgnet.com/1007-9327/full/v31/i45/112926.htm
- DOI: https://dx.doi.org/10.3748/wjg.v31.i45.112926