Apoptosis of human gastric adenocarcinoma cells induced by β-ionone

Math 1 Math(A1).

Figure 1 Proliferation kinetics of SGC-7901 cells treated with β-ionone at various concentrations.

Figure 2 β-ionone-induced apoptosis in SGC-7901 cells stained with Hoechst-33258 (× 400). A: control SGC-7901 cells, B: ex-perimental cells treated with β-ionone showing nuclear shrink-age or fragmentation.

Figure 3 Ultrastructural changes of SGC-7901 cells treated with 100 μmol/L β-ionone for 24 h (× 15000). A: SGC-7901 cells in the control group, B: experimental SGC-7901 cells treated with β-ionone showing early changes of apoptosis in which nuclear chromatin condensation and cell shrinkage were observed.

Figure 4 Apoptotic cells induced by β-ionone (200 μmol/L 48 h) in SGC-7901 cells detected TUNEL assay (× 400).