©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 28, 2026; 32(8): 115654
Published online Feb 28, 2026. doi: 10.3748/wjg.v32.i8.115654
Published online Feb 28, 2026. doi: 10.3748/wjg.v32.i8.115654
Ischemic duodenal injury due to systemic lupus erythematosus: A case report
Yung Kil Kim, Hae Il Jung, Hyeyoung Kim, Sang Ho Bae, Department of Surgery, Soonchunhyang University Cheonan Hospital, Cheonan 31151, South Korea
Author contributions: Kim YK led data acquisition, case organization, figure preparation, literature review, and manuscript drafting; Bae SH oversaw surgical management, provided expert interpretation, and critically reviewed the manuscript; Jung HI contributed pathological evaluation and manuscript revision; Kim H contributed rheumatologic assessment, interpretation of clinical progression, and manuscript revision; all authors have read and approved the final version of the manuscript.
Informed consent statement: This case report was conducted in accordance with the institutional ethical standards and principles of the Declaration of Helsinki (revised in 2013). Written informed consent was obtained from the patient for the publication of the case details and accompanying images.
Conflict-of-interest statement: The Soonchunhyang University Research Fund provides a publication-support incentive that is awarded after acceptance of an article in an international journal. This incentive is a recognition award from the institution rather than research funding, and it is not related in any way to study design, data collection, analysis, or manuscript preparation. The authors declare no other conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised in accordance with these guidelines.
Corresponding author: Sang Ho Bae, MD, PhD, Professor, Department of Surgery, Soon
Received: October 22, 2025
Revised: December 11, 2025
Accepted: December 31, 2025
Published online: February 28, 2026
Processing time: 112 Days and 21.3 Hours
Revised: December 11, 2025
Accepted: December 31, 2025
Published online: February 28, 2026
Processing time: 112 Days and 21.3 Hours
Core Tip
Core Tip: Duodenal involvement in lupus enteritis is exceptionally rare and may progress to ischemia requiring surgery. Early recognition is critical, as delayed diagnosis can be life-threatening. Because it is often difficult to predict whether lupus enteritis will respond to steroids or instead progress to ischemia, a multidisciplinary approach and timely decision-making are essential. In this case, early duodenal resection and duodenojejunostomy prevented further deterioration, and post