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Meta-Analysis
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 14, 2026; 32(6): 114600
Published online Feb 14, 2026. doi: 10.3748/wjg.v32.i6.114600
Effects of bariatric surgery on obesity associated gastroesophageal reflux disease: Insights from a systematic review and network meta-analysis
Ying Xing, Wen-Mao Yan, Ri-Xing Bai
Ying Xing, Wen-Mao Yan, Ri-Xing Bai, Department of General Surgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
Author contributions: Xing Y designed the study and analyzed the data; Yan WM collected the data and write the manuscript; Bai RX revised the manuscript; all of the authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ri-Xing Bai, MD, PhD, Department of General Surgery, Beijing Tiantan Hospital, Capital Medical University, No. 119 South 4th Ring West Road, Fengtai District, Beijing 100070, China. brx5168@163.com
Received: September 24, 2025
Revised: November 19, 2025
Accepted: December 23, 2025
Published online: February 14, 2026
Processing time: 131 Days and 22.6 Hours
Core Tip

Core Tip: For patients with obesity and gastroesophageal reflux disease (GERD), Roux-en-Y gastric bypass and one-anastomosis gastric bypass are more effective than sleeve gastrectomy for weight loss and GERD control, with Roux-en-Y gastric bypass demonstrating a 99% possibility as the most effective in GERD remission. Addition of antireflux procedures did not improve GERD outcome. It may also increase complications when sleeve gastrectomy is chosen, raising the question of whether or not an additional antireflux procedure is necessary. These findings provide more evidence to inform surgical decision-making for patients with obesity and GERD.