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World J Gastroenterol. Aug 21, 2026; 32(31): 119592
Published online Aug 21, 2026. doi: 10.3748/wjg.119592
Published online Aug 21, 2026. doi: 10.3748/wjg.119592
Spatiotemporal trends in pancreatic cancer incidence from 2013 to 2023 in Gansu Province, Northwest China: A regional study
Yan-Mei Gu, Jie Liu, Ying-Ying Wang, Gang-Li Liu, Yuan-Yuan Li, Xiao-Mei Li, Yang Zhao, Hui-Juan Cheng, Jun Zhao, Yu-Min Li, Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, Gansu Province, China
Yu-Min Li, Gansu Province Key Laboratory of Environmental Oncology, Lanzhou University, Lanzhou 730030, Gansu Province, China
Author contributions: Gu YM and Li YM designed the study and acquired funding; Gu YM and Liu J were responsible for developing the methodology; Wang YY, Liu GL, Li YY, and Li XM participated in the formal analysis and investigation; Gu YM wrote the original draft; Gu YM, Zhao Y, Cheng HJ, Zhao J, and Li YM participated in the article review and editing. All authors have read and approved the final version to be published.
Supported by the Cuiying Science and Technology Innovation Program Project of the Second Hospital of Lanzhou University, No. CY2022-MS-A18; and the Chief Scientist Project of the Science and Technology Department of Gansu Province, No. 22JR9KA002.
Institutional review board statement: This study adhered to the principles of the Declaration of Helsinki. This study was approved by the Ethics Committee of the Lanzhou University Second Hospital (No. 2022A-670).
Informed consent statement: According to national regulations, the Ethics Committee of the Lanzhou University Second Hospital did not require the use of informed consents.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The data, models and the code that support the findings of this study are available from the corresponding author upon request.
Corresponding author: Yu-Min Li, MD, PhD, Chief Physician, Professor, Department of General Surgery, Lanzhou University Second Hospital, No. 82 Cuiying Gate, Lanzhou 730030, Gansu Province, China. liym@lzu.edu.cn
Received: February 6, 2026
Revised: March 6, 2026
Accepted: April 16, 2026
Published online: August 21, 2026
Processing time: 179 Days and 16.6 Hours
Revised: March 6, 2026
Accepted: April 16, 2026
Published online: August 21, 2026
Processing time: 179 Days and 16.6 Hours
Core Tip
Core Tip: Using province-level multi-center hospital surveillance data from 262 hospitals in Gansu Province, China from 2013 to 2023, we quantified pancreatic cancer incidence trends and mapped county-level spatiotemporal clusters. It was found that age-standarded incidence increased from 2.39 per 100000 people to 3.23 per 100000 population, with consistently higher rates in men and older adults. Spatial autocorrelation and SaTScan revealed persistent high-risk hotspots concentrated in the Hexi region, and an increasing burden in the Dwb climate zone. These results provide an evidence for targeted prevention, earlier diagnosis, and resource allocation in high-risk counties.