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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 7, 2025; 31(45): 111643
Published online Dec 7, 2025. doi: 10.3748/wjg.v31.i45.111643
Published online Dec 7, 2025. doi: 10.3748/wjg.v31.i45.111643
Metabolic dysfunction-associated steatotic liver disease in Egypt: Epidemiology, risk factors and management challenges
Walaa Abdelhamed, Department of Endemic Medicine, Sohag University, Sohag 14322, Egypt
Mona Amin, Department of Internal Medicine, Cairo University, Cairo 11451, Egypt
Imam Waked, Department of Hepatology, National Liver Institute, Menoufia University, Menoufia 35211, Egypt
Mohamed El-Kassas, Department of Endemic Medicine, Faculty of Medicine, Helwan University, Cairo 11795, Egypt
Mohamed El-Kassas, Applied Science Research Center, Applied Science Private University, Amman 11931, Jordan
Author contributions: El-Kassas M conceptualized the idea; Abdelhamed W drafted the manuscript; Amin M and Waked I revised and edited the final manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mohamed El-Kassas, PhD, Doctor, Department of Endemic Medicine, Faculty of Medicine, Helwan University, Ain Helwan, Cairo 11795, Egypt.
Received: July 6, 2025
Revised: August 22, 2025
Accepted: October 27, 2025
Published online: December 7, 2025
Processing time: 151 Days and 20.1 Hours
Revised: August 22, 2025
Accepted: October 27, 2025
Published online: December 7, 2025
Processing time: 151 Days and 20.1 Hours
Core Tip
Core Tip: Egypt faces one of the highest metabolic dysfunction-associated steatotic liver disease (MASLD) burdens globally, yet disease awareness and access to care remain critically limited. Recognizing MASLD as a national health priority and integrating it into non-communicable disease strategies through population-based screening, lifestyle interventions, and provider education, offers a scalable model for other high-risk, resource-constrained settings.